Abstract:
Quinoxaline compounds are essential nitrogen containing heterocyclic compounds of various biological properties and have several pharmaceutical applications. In this work, several precursors to be used in quinoxaline cyclization were synthesized from diamine- and tetra-aminobenzene hydrochloride precursors. Our group added several substituents to phenylenediamine or used directly 1,2,4,5-Benzenetetramine tetrahydrochloride before a coupling reaction with 1,2-Acenaphthylenedione. The systematic characterization of the quinoxaline derivatives and final products were done via 1H-NMR and13C-NMR.
