Browsing Ph.D. Theses by Title

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  • 3-D gamma knife distribution by normoxic gel dosimetry near tissue inhomogeneties 
    İşbakan, Fatih. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2005., 2005.)
    The primary goal in this study was to investigate the three dimensional dose distributions, near the areas of tissue inhomogeneities, in Gamma Knife Radiosurgery with the normoxic gel dosimetry. Following irradiation, when ...
  • A hybrid biological/in silico neural network based brain-machine interface 
    Kocatürk, Mehmet. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2015., 2015.)
    Brain-machine interfaces (BMIs) aim to improve the lives of individuals with neurological disease or injury, by opening new information transfer channels between brain tissue and prosthetic actuators. In a majority of the ...
  • A macro-structural characteristic of brain white matter :|'dispersion' with its clinical and technical applications 
    Demir, Ali. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2020., 2020.)
    The main goal of this thesis is to find distinct macro-structural characteristics of brain white matter in the case of psychosis, where development of diagnostic imaging measures is necessary for early diagnosis and ...
  • A model of active and attentive vision 
    Soyer, Çağatay. (Thesis (Ph.D.) - Bogazici University. Institute of Biomedical Engineering, 2002., 2002.)
    Biological vision systems explore their environment by allocating their resources to interesting parts of a scene, using both physical and mental attention mechanisms. The result of this active and attentive vision behavior ...
  • A neurovascular coupling model based on nitric oxide and carbon dioxide and its validation with two-photon microscopy imaging 
    Yücel, Meryem Ayşe. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2010., 2010.)
    Understanding neurovascular coupling is of paramount importance since while a normal coupling is vital for a healthy functioning brain, the impairment in coupling is the underlying factor of many neurodegenerative diseases. ...
  • A study in cultured neuronal networks 
    Bayat, Fazıl Kemal. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2021., 2021.)
    In this study, two platforms, combining multi-electrode arrays and optogenetic methods, were developed to study living neural networks in vitro. Both platforms, which included stimulation of neural networks developed in ...
  • Accuracy improvements of NIRS and investigation of muscle oxidative metabolism 
    Şayli, Ömer. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2009., 2009.)
    In the rst part of the thesis, the e ect of fat layer on continuous wave near infrared spectroscopy (cw-NIRS) measurements were investigated in detail, both in terms of underestimation error (caused by homogeneous medium ...
  • Advanced computational tools for real-time MR imaging 
    Saybaşılı, Haris. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2009., 2009.)
    Real-time Magnetic Resonance Imaging (MRI) has the potential of successfully guiding interventional applications. Overall, the requirements of real-time MRI can be categorized as: (i) fast data acquisition, (ii) fast image ...
  • An optoelectronic system for device localization in interventional MRI 
    Tümer, Murat. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2015., 2015.)
    In active catheter tracking, a microcoil directly connected to the MRI system and positioned at the distal end of the catheter is employed for localization. The peaks in the frequency spectrum of the acquired MR signal ...
  • Antibacterial photodynamic therapy with indocyanine green and near-infrared light 
    Topaloğlu, Nermin. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2014., 2014.)
    Increase in antibiotic-resistance is a worldwide health problem which may result in septicemia and subsequent death in recent years. Some of these deaths are caused by nosocomial, burn or chronic wound infections. Photodynamic ...
  • Application of newborn jaundice determination and design of a noninvasive bilirubinometer 
    Karamavuş, Yunus. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2019., 2019.)
    Newborn jaundice (hyperbilirubinemia), which is seen in 65% of healthy newborns, is usually a harmless condition and passes without any treatment. However, 5% of the jaundiced babies develop kernictures which may cause ...
  • Artificial tactile sensation by microstimulation of the hindpaw representation in the primary somatosensory cortex of behaving rats 
    Devecioğlu, İsmail. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2016., 2016.)
    In this thesis, rats were trained to detect the presence or absence of bursts of mechanical sinusoidal vibrations (duration: 0.5 s, zero-to-peak amplitude: 200 m, frequency: 40 Hz) delivered to the volar surface of their ...
  • Assessment of active state titin's effects on muscle mechanics using finite element modeling 
    Çankaya, Alican Onur. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2022., 2022.)
    Calcium dependent mechanical behaviors characterize titin's contribution to force production in three-myo lament paradigm: (1) Sti ening of PEVK (Proline, Glutamate, Valine, Lysine) segment, and (2) reduction of free-spring ...
  • Assessment of effects of botulinum toxin on muscle mechanics 
    Türkoğlu, Ahu Nur. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2015., 2015.)
    E ects of widely used Botulinum toxin (BTX) treatment on muscular mechanics are highly important, but their mechanism and time course are not well understood. Present thesis is focused on mechanical mechanism of BTX treatment ...
  • Assessment of local muscle deformations using multi-modal imaging and finite element modeling 
    Pamuk, Uluç. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2019., 2019.)
    In vivo assessment of muscle deformations, including influence of non-muscular tissues such as NVTs, aponeuroses, fasciæ or overlying skin, is key due to functional relevance of tissue connectivity within limb. In integral ...
  • Bioimpedance spectroscopy in prediction of type I osteoporosis in menopaused women 
    Matur, Fırat. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2021., 2021.)
    Bone mineral density (BMD) is a measure of survival for men and women, and it is used to diagnose Osteoporosis that can be diagnosed and treated with an e ective screening. We measured bioimpedance spectroscopy (BIS) ...
  • Biological effects of electromagnetic fields at mobile telecommunication frequencies 
    Yürekli, Ali İhsan. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2006., 2006.)
    The increasing use of cellular phones and increasing number of base stations are becoming awidespread source of non-ionizing electromagnetic radiation. The immediate biological effectof electromagnetic (EM) radiation is ...
  • Biomedical applications of sharkskin mimicked polymeric membranes 
    Rostami, Sabra. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2022., 2022.)
    Infection is one of the biggest challenges of implantable biomaterials. The diffi culty of eliminating implant-associated infection imposes a huge burden on the patient's life quality aside from the considerable financial ...
  • Biomimetic polydimethylsiloxane cell substrate design for enhanced in vitro cellular behavior 
    Öztürk, Meftune Özgen. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2021., 2021.)
    Recent developments in cell-based therapies and toxicological investigations re veal the need for well-designed, stable and flexible cell substrates. Mimicking the natu ral cellular microenvironment by altering cell substrate ...
  • Biophysical approaches for modulating neural differentiation 
    Özgün, Alp. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2021., 2021.)
    Neural differentiation of stem cells is central to regenerative strategies towards neurodegenerative diseases. The vast majority of literature shows chemical, biochem ical and genetic approaches to control and utilize ...

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