Browsing Ph.D. Theses by Issue Date

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  • Photofrin and indocyanine green-mediated photodynamic therapy in cancer treatment 
    Bozkulak, Özgüncem. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2010., 2010.)
    Photodynamic therapy (PDT) is a minimally invasive therapeutic approach for clinical treatment of cancer. PDT-mediated oxidative stress leads to cell death and can elicit the expression of genes associated with cell survival, ...
  • Design and development of thulium laser system for medical applications 
    Bilici, Temel. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2012., 2012.)
    The Thulium (Tm:YAP) laser is suitable for medical applications due to strong absorption in water. In this thesis, a computer controlled Tm:YAP laser system with a power output up to 1 W and emission wavelength of 1980 nm ...
  • Neuroimaging of brain activity using spatio-temporal signal modelling 
    Duru, Adil Deniz. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2012., 2012.)
    Functional neuroimaging enables us to obtain information about how the brain responds to cognitive and/or emotional tasks. Neuroimaging of brain activity requires spatio-temporal modelling of measured electrical and/or ...
  • Revealing gene interactions using Bayesian Networks 
    İşçi, Şenol. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2012., 2013.)
    High throughput biological data (HTBD) targeting understanding of biochemical interactions in the cell can best be analyzed, and explained within the context of networks and pathways. Such data generally represents stochastic ...
  • Mechanics of spastic muscle and effects of treatment techniques: assessments with intra-operative and animal experiments 
    Ateş, Filiz. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2013., 2013.)
    Present thesis is focused on mechanics of spastic human muscles and the e ects of widely used treatment methods in the context of the determinant role of epimuscular myofascial force transmission (EMFT). A novel intra-operative ...
  • Detection and assessment of cardiac patent foramen ovale 
    Parlak, İsmail Burak. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2013., 2013.)
    Arterial microemboli are gas lled structures which are formed in intravascular and extravascular environment. They are characterized in spherical or ellipsoid forms which would cause diseases in a broad range from stroke ...
  • Diffusion tensor fiber tracking with self-organizing feature maps 
    Göksel, Dilek. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2013., 2013.)
    The diffusion tensor imaging (DTI) is unique in its ability to estimate the white matter (WM) ber tracts in vivo noninvasively. The post-processing of DT images needs proper image analysis and visualization tools. However, ...
  • Effects of mechanical and temporal parameters on tactile psychophysical responses 
    Yıldız, Mustafa Zahid. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2013., 2013.)
    Tactile feedback is becoming more important in clinical devices and engineering. Therefore, studies on basic sensory processing in the somatosensory system are essential. In this thesis, the mechanical and temporal parameters ...
  • Clinical grade active guidewire design for cardivascular interventional MRI 
    Sönmez, Merdim. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2013., 2013.)
    In cardiovascular interventions, magnetic resonance imaging (MRI) can be used as an alternative to X-ray uoroscopy to address problems such as soft tissue contrast and exposed ionized radiation. In recent years, advances ...
  • Antibacterial photodynamic therapy with indocyanine green and near-infrared light 
    Topaloğlu, Nermin. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2014., 2014.)
    Increase in antibiotic-resistance is a worldwide health problem which may result in septicemia and subsequent death in recent years. Some of these deaths are caused by nosocomial, burn or chronic wound infections. Photodynamic ...
  • Time-frequency and time-scale analysis of non-stationary biomedical signals 
    Serbes, Görkem. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2014., 2014.)
    Fourier transform (FT), which assumes that the analyzed signal is stationary, is not entirely appropriate to analyze biomedical signals since they are in non-stationary nature. To overcome this drawback, FT can be applied ...
  • Monitoring depth of anesthesia through measurement of phase coupling among spontaneous EEG rhythms 
    Mousavi, Seyed Mortaza. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2014., 2014.)
    Awareness during general anesthesia for its serious psychological e ects on patients and some juristically problems for anesthetists has been an important challenge during past decades. Monitoring depth of anesthesia is a ...
  • MRI assessment of in vivo epimuscular myofascial force transmission 
    Yaman, Alper. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2014., 2014.)
    Recent developments have been evolving magnetic resonance imaging (MRI) to a combined tool in order to assess human anatomy and physiology in vivo. In the present thesis 3D high resolution anatomic and di usion weighted ...
  • A hybrid biological/in silico neural network based brain-machine interface 
    Kocatürk, Mehmet. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2015., 2015.)
    Brain-machine interfaces (BMIs) aim to improve the lives of individuals with neurological disease or injury, by opening new information transfer channels between brain tissue and prosthetic actuators. In a majority of the ...
  • Tensor analysis of neuroimaging data 
    Karahan Şenvardar, Esin. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2015., 2015.)
    Acquisition of large amounts of data in neuroimaging research requires development of new methods that can disentangle the underlying information and reveal the features related to cognitive processes. This thesis attempts ...
  • Nonlinear state and parameter estimation of the hemodynamic model using fMRI bold signal 
    Aslan, Serdar. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2015., 2015.)
    The joint estimation of the parameters and the states of the hemodynamic model from the blood oxygen level dependent (BOLD) signal is a challenging problem. In the functional magnetic resonance imaging (fMRI) literature, ...
  • An optoelectronic system for device localization in interventional MRI 
    Tümer, Murat. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2015., 2015.)
    In active catheter tracking, a microcoil directly connected to the MRI system and positioned at the distal end of the catheter is employed for localization. The peaks in the frequency spectrum of the acquired MR signal ...
  • Assessment of effects of botulinum toxin on muscle mechanics 
    Türkoğlu, Ahu Nur. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2015., 2015.)
    E ects of widely used Botulinum toxin (BTX) treatment on muscular mechanics are highly important, but their mechanism and time course are not well understood. Present thesis is focused on mechanical mechanism of BTX treatment ...
  • Investigation of oscillatory mechanisms and thalamo-cortical circuitry of the visual system by simultaneous EEG-fMRI 
    Bayram, Ali. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2015., 2015.)
    Neural oscillation is an indispensable phenomena in the functioning of the cortical networks. Evoked neural oscillations triggered by external rhythmic stimulation mimic spontaneous ongoing oscillations, thus could shed ...
  • Laser biostimulation and monitorization of wound healing by means of bioimpedance measurements 
    Solmaz, Hakan. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2016., 2016.)
    Wound healing is critically important for the quality of life. Substantial number of patients suffering from non-healing chronic wounds and having serious difficulties in their daily life are reported in wound healing ...

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