Browsing Ph.D. Theses by Title

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  • Models to assess the quality of stored erythrocyte suspensions by diffuse reflectance measurements 
    Can, Osman Melih. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2020., 2020.)
    Legislation in transfusion medicine define hemolysis level as the quality measure for erythrocyte suspensions (ES). Since the golden standard test for hemolysis is destructive and causing wastage of units, the hemolysis ...
  • Monitoring depth of anesthesia through measurement of phase coupling among spontaneous EEG rhythms 
    Mousavi, Seyed Mortaza. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2014., 2014.)
    Awareness during general anesthesia for its serious psychological e ects on patients and some juristically problems for anesthetists has been an important challenge during past decades. Monitoring depth of anesthesia is a ...
  • MRI assessment of in vivo epimuscular myofascial force transmission 
    Yaman, Alper. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2014., 2014.)
    Recent developments have been evolving magnetic resonance imaging (MRI) to a combined tool in order to assess human anatomy and physiology in vivo. In the present thesis 3D high resolution anatomic and di usion weighted ...
  • Multimodal investigation of fMRI and fNIRS derived breath hold BOLD signals with an expanded balloon model 
    Emir, Uzay Emrah. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2008., 2008.)
    Multimodal investigation of blood oxygenation level-dependent (BOLD) signal, using both functional near infrared spectroscopy (fNIRS) and functional magnetic resonance imaging (fMRI), may give further insight to the ...
  • Neuroimaging of brain activity using spatio-temporal signal modelling 
    Duru, Adil Deniz. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2012., 2012.)
    Functional neuroimaging enables us to obtain information about how the brain responds to cognitive and/or emotional tasks. Neuroimaging of brain activity requires spatio-temporal modelling of measured electrical and/or ...
  • Nonlinear state and parameter estimation of the hemodynamic model using fMRI bold signal 
    Aslan, Serdar. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2015., 2015.)
    The joint estimation of the parameters and the states of the hemodynamic model from the blood oxygen level dependent (BOLD) signal is a challenging problem. In the functional magnetic resonance imaging (fMRI) literature, ...
  • Novel biopsy needle and assisted robotic system design for prostate biopsy procedure under MRI 
    Mahçiçek, Davut İbrahim. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2021., 2021.)
    Prostate cancer (PCa) is one of the most common cancer type among men. The mortality rate for prostate cancer is signi cantly high compared to other common cancer types which makes it even more concerning for elderly males. ...
  • Optimizing the accuracy of tumor segmentation in pet for radiotherapy planning using blind deconvolution method 
    Koç, Alpaslan. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2019., 2019.)
    Tumor segmentation accuracy greatly affects the effectiveness of radiotherapy procedures. Maximizing the segmentation accuracy has high medical significance in order to deliver the highest radiation dose to the target volume ...
  • Photobiomodulation on human osteoblasts and osteogenic differentiation of adipose-derived stem cells 
    Bölükbaşı, Gamze. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2017., 2017.)
    The present in vitro comparative study evaluated parameters of osteogenesis under the influence of photobiomodulation (PBM). PBM uses light in the visible and near-infrared spectrum to induce a non-thermal process and to ...
  • Photodynamic therapy with upconversion nanoparticles 
    Güleryüz, Burcu. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2022., 2022.)
    Photodynamic therapy (PDT) is an alternative approach to conventional meth ods (i e. chemotherapy and radiotherapy) that can be utilized to treat various cancers with less side effects. However, PDT has some restrictions ...
  • Photofrin and indocyanine green-mediated photodynamic therapy in cancer treatment 
    Bozkulak, Özgüncem. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2010., 2010.)
    Photodynamic therapy (PDT) is a minimally invasive therapeutic approach for clinical treatment of cancer. PDT-mediated oxidative stress leads to cell death and can elicit the expression of genes associated with cell survival, ...
  • Prediction of psychophysical responses from spike recordings in rat sensorimotor cortex by using Bayesian models 
    Öztürk, Sevgi. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2021., 2021.)
    In this thesis, we studied the fundamental question in neuroscience: how per ception is built based on the sensory stimuli from the physical world and turned into motor actions in the face of uncertain neural representations. ...
  • Psychophysical evaluation of a sensory feedback system for prosthetic hands 
    Karakuş, İpek. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2020., 2020.)
    In this study, a vibrotactile sensory feedback system was designed and tested in accordance with the discrete event-driven sensory feedback control paradigm. Novel approaches were applied in terms of data processing and ...
  • Revealing gene interactions using Bayesian Networks 
    İşçi, Şenol. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2012., 2013.)
    High throughput biological data (HTBD) targeting understanding of biochemical interactions in the cell can best be analyzed, and explained within the context of networks and pathways. Such data generally represents stochastic ...
  • Skeletal muscle mechanics and spasticity management :|human and animal experiments 
    Kaya Keleş, Cemre Su. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2022., 2022.)
    Being the most common motor disability in childhood, cerebral palsy (CP) describes a movement disorder for which the exact underlying mechanism is unclear, and no cure is available. Yet, local injection of botulinum toxin ...
  • Skin tissue welding with near infrared lasers: investigation of the optimal parameters 
    Tabakoğlu, Haşim Özgür. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2010., 2010.)
    Laser tissue welding/soldering is an alternative to conventional closure techniques in surgery. In the present study, the closure capability and the contribution to recovery period of laser welding techniques were investigated ...
  • SOD1 A4V mutation increases Nav1.3 channel excitability on xenopus laevis oocyte 
    Kubat, Elif. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2016., 2016.)
    Amyotrophic lateral sclerosis (ALS) is a lethal, paralytic disease caused by degeneration of motor neurons in the spinal cord, brain stem and motor cortex. Mutations in the gene encoding copper/zinc superoxide dismutase ...
  • Statistical analysis of cognitive signals measured by fNIRS 
    Çifçi, Rifat Koray. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2008., 2008.)
    Further standardization in signal processing tools is needed in the area of functional near infrared spectroscopy (fNIRS) before it is recognized as a reliable neuroimaging modality. This thesis study attempts to present ...
  • Strategies to increase photodynamic theraph efficacy on conventional and complex in vitro cancer models 
    Ruhi, Mustafa Kemal. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2019., 2019.)
    Cancer is one of the leading causes of death worldwide. Due to the side-effects and inefficacy of the conventional cancer treatment methods, alternative modalities are researched. Oneofthealternatives, PhotodynamicTherapy(P ...
  • Targeting tumor microenvironment to improve immunotherapy responses 
    Damgacı Ertürk, Sultan. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2020., 2020.)
    The acidic microenvironment of solid tumors has suppressing effects on immune cells, accordingly immunotherapy responses. This thesis composed of two main studies as measuring tumor pH with non-invasive methods using ...

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