Browsing Ph.D. Theses by Issue Date

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  • pH and temperature dependence of the rate of dissolution of AgIO3 
    Uyanık, Ömer Lütfi. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 1984., 1984.)
    In this thesis a theory based ona dissolution model was checked experimentally. The theory which is developed by B.V. Enüstün expresses the initial rate of dissolution for a 1:1 type ionic solid in terms of the model ...
  • Segmental orientation and conformational dynamics of polymer chains 
    Haliloğlu, Türkan. (Thesis (Ph.D)- Bogazici University. Institute for Graduate Studies in Science and Engineering, 1992., 1992.)
    Various remarkable features of polymers, as compared with metallic and inorganic materials, arise from the fact that macromolecules can take up various conformations. The study of macromolecular conformations and dynamics ...
  • Optimal resilient retrofit design of heat-exchanger networks 
    Konukman, Alp Er Şevki. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 1996., 1996.)
    A new index, called Design Resiliency Index, which numerically indicates the size of feasible region in terms of uncertain source-temperature or flowrates for the fixed design parameters of a network structure, is proposed. ...
  • Efficient computational models and methods for investigating local polymer dynamics 
    Baysal, Canan. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 1996., 1996.)
    Local Phenomena related to the isomerization of torsional angles in polymers are studied using computational tools with emphasis on the problem of efficiency. Molecular and Brownian Dynamics, Dynamic Rotational Isomeric ...
  • Fermentation and recovery of EcoRI endonuclease using two different genetically engineered E.coli strains 
    Yıldır (Tamerler), Candan. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 1997., 1997.)
    A small scale procedure developed for the purification of EcoRI restriction enzyme has been applied to two different overproducing E.coli strains. The final purification yields obtained are 1.3x105 U/g cells for E.coli ...
  • Fermentation characteristics of four genetically engineered Saccharomyces cerevisiae strains 
    Birol (Deniz), Gülnur. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 1997., 1997.)
    The production of ethanol from starch has been investigated in four genetically modified Saccharomyces cerevisiae strains (YPG/AB, YA7, YPG/MM and YPB-G). Three of the four strains produce the Aspergillus awamori glucoamylase ...
  • A process for the deterpenation of essential oils by extraction/adsorption/desorption using supercritical carbon dioxide 
    Eskinazi, Orli A. (Thesis (Ph.D.)- Bogazici University. Institute for Graduate Studies in Science and Engineering, 1999., 1999.)
    The main purpose of this study was to establish a supercritical-fluid-aided process in order to enhance the quality of essential-oils products through the removal of the monoterpene (MT) hydrocarbons. The example oil chosen ...
  • Production of Taq I restriction and modification enzymes by using two different expression systems 
    Toksoy, Ebru. (Thesis (Ph.D)- Bogazici University. Institute for Graduate Studies in Science and Engineering, 2000, 2000.)
    Taq I restriction-modification system has been cloned and expressed using two different expression systems. In the first system, Taq I restriction endonuclease was expressed as a fusion protein with the maltose-binding ...
  • Analysis of folding kinetics for simplified model proteins 
    Özkan, Ş. Banu. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2001., 2001.)
    The conformational stochastics of simplified model chains that show an apparent two-state kinetics was explored.. A fundamental question addressed in the present analysis is to understand if the folding takes place through ...
  • Computational and experimental investigation of catalytic hydrocarbon fuel processing for autothermal hydrogen production 
    Avcı, Ahmet Kerim. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2003., 2003.)
    Catalytic conversion of hydrocarbon fuels within the context of the operation of a fuel processor for supplying hydrogen to vehicular and stationary fuel cells is investigated using computer-based modeling/simulation studies ...
  • Integrated analysis of metabolome profiles and gene expression in respiratory deficient deletion mutants of Saccharomyces Cerevisiae 
    Pir, Pınar. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2005., 2005.)
    A study on transcriptional and metabolic response of S. cerevisiae cells toenvironmental and genetic perturbations was made. Deletion mutants with BY4743backgound were used. Homozygous deletion mutants ho/ho (reference ...
  • Stoichiometric models in metabolic systems biology of yeast 
    Çakır, Tunahan. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2006., 2006.)
    A system-level analysis of Saccharomyces cerevisiae metabolism was performed through integration of stoichiometric modeling and high-throughput ‘omics’ data. A bridge between metabolic networks and transcriptomics was built ...
  • System biology of yeast signal transduction 
    Arğa, Kazım Yalçın. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2007., 2007.)
    Reconstruction of protein interaction networks that represent groups of proteins contributing to the same cellular function is a key step towards quantitative studies of signal transduction pathways. In the present study, ...
  • Supercritical carbon dioxide immobilization of glucose oxidase on conducting polymers towards biosensor production 
    Talay, Defne Kayrak. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2007., 2007.)
    In this work, glucose oxidase (GOX) is immobilized on conducting polymer matrices (polypyrrole film, PPY; polyurethane/polpyrrole composite foam and film, PU/PPY) via Supercritical Fluid Immobilization (SFI) for further ...
  • Mixed-resolution elastic network models for biological supramolecules 
    Levitas, Ayşe Özge Kürkçüoğlu. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2008., 2008.)
    Mixed coarse-graining approach has been recently introduced to the elastic network model to enable the modeling of a protein’s native conformation with regions of high- and low-resolution. In this model, each node of the ...
  • Utilization of carbon dioxide and methane via catalytic reforming reactions 
    Aydınoğlu, Şeyma Özkara. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2008., 2008.)
    The overall purpose of this research study was to investigate new catalysts to produce synthesis gas via CO2 reforming of methane under optimized reaction conditions. The thesis consists of four parts. In the first part ...
  • Recognition and binding processes in HIV-1 protease 
    Özer, Asuman Nevra. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2008., 2008.)
    HIV-1 protease is a drug target against AIDS and understanding its molecu- lar recognition processes is important in development of drugs. Here, the combined computational methodologies used put three different perspectives ...
  • Conformational transitions of proteins explored by Monte Carlo simulations integrated with collective modews 
    Çarşıbaşı, Nigar Kantarcı. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2009., 2009.)
    Elucidation of conformational transitions between open/closed or free/bound states of proteins sheds light on the mechanism of their action. In this thesis, a new technique (ANM-MC) is proposed, in which collective modes ...
  • Development of a systems based modular approach to link complex diseases 
    Rende, Deniz. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2010., 2010.)
    A novel systems based modular approach was developed in this study to investigate the shared underlying mechanisms of three prevalent complex disorders: cardiovascular disease (CVD), Type 2 diabetes (T2D) and Alzheimer‘s ...
  • A theoretical study on catalytic steps of hydrogen production and purification 
    Sümer, Aslıhan. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2010., 2010.)
    The aim of this thesis is to obtain information on catalytic activity of transition metals used in different steps of hydrogen production and purification. Density functional theory calculations with periodic slabs have ...

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