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Browsing Ph.D. Theses by Author "Haliloğlu, Türkan."

Browsing Ph.D. Theses by Author "Haliloğlu, Türkan."

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  • An integrated computational and experimental approach to allosteric control mechanism of biomolecular processes 
    Sümbül, Fidan. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2016., 2016.)
    Proteins are exible and dynamic in nature and can undergo structural rearrangements to perform their functions. The motivation of this thesis is to develop a novel integrated computational and experimental approach to ...
  • Calcium signaling system in multiple species : structural and functional analyses of protein interaction networks 
    Tiveci, Senem. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2011., 2011.)
    Calcium is an important second messenger to have a key role in many processes occurring in the cell. Understanding the mechanisms of calcium signaling in multiple species i.e. yeast and worm may help to untangle calcium ...
  • Computational and experimental investigations into the mechanism of functional motion in biomolecular systems 
    Fas, Ayşe Burcu Aykaç. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2016., 2016.)
    The seemingly random fluctuations that proteins exhibit in their native states actually harbor major contributions from the global/cooperative motions they undergo during functional transitions. Computationally efficient, ...
  • Conformational transitions of proteins explored by Monte Carlo simulations integrated with collective modews 
    Çarşıbaşı, Nigar Kantarcı. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2009., 2009.)
    Elucidation of conformational transitions between open/closed or free/bound states of proteins sheds light on the mechanism of their action. In this thesis, a new technique (ANM-MC) is proposed, in which collective modes ...
  • Recognition and binding processes in HIV-1 protease 
    Özer, Asuman Nevra. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2008., 2008.)
    HIV-1 protease is a drug target against AIDS and understanding its molecu- lar recognition processes is important in development of drugs. Here, the combined computational methodologies used put three different perspectives ...
  • Segmental orientation and conformational dynamics of polymer chains 
    Haliloğlu, Türkan. (Thesis (Ph.D)- Bogazici University. Institute for Graduate Studies in Science and Engineering, 1992., 1992.)
    Various remarkable features of polymers, as compared with metallic and inorganic materials, arise from the fact that macromolecules can take up various conformations. The study of macromolecular conformations and dynamics ...
  • Systems-level understanding of copper effect in Saccharomyces cerevisiae 
    Öç, Şebnem. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2019., 2019.)
    Copper is a crucial trace element for all living systems as it is required for the proper functioning of several biological processes. Copper homeostasis, which governs the mechanisms of copper uptake, delivery, utilization, ...

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