Arşiv ve Dokümantasyon Merkezi
Dijital Arşivi

Anatomy of antidepressant effect of light: the role of the BNST lesions

Basit öğe kaydını göster

dc.contributor Graduate Program in Psychology.
dc.contributor.advisor Canbeyli, Reşit.
dc.contributor.author Avlar, Billur.
dc.date.accessioned 2023-03-16T12:20:09Z
dc.date.available 2023-03-16T12:20:09Z
dc.date.issued 2008.
dc.identifier.other PSY 2008 A85
dc.identifier.uri http://digitalarchive.boun.edu.tr/handle/123456789/17164
dc.description.abstract The aim of the present study was to shed light on the anatomy of antidepressant effect of bright light therapy. In line with this, lesions of the Bed Nucleus of the Stria Terminalis (BNST) which is implicated as an important relay area in mediating stress related circuitry in the brain, or sham operations were done in male Wistar rats. Nine weeks later, a single 10 min, 200 watt, 1350 lux bright light stimulus was administered at ZT21 (04:00) to lesioned (LL) or sham operated rats (SL). Control group animals; either lesioned (LC) or sham operated (SC) did not receive light stimulus. Behavioral despair was assessed by consecutive forced swim tests. The results replicated the aggravation of the immobility behavior in LC group and demonstrated an ameliorative effect of the light even in the presence of the BNST lesion (LL). These findings suggest that the BNST lesions confined to mostly the medial division do not have an integral role in mediating the antidepressant effects of light.
dc.format.extent 30cm.
dc.publisher Thesis (M.A.)-Bogazici University. Institute for Graduate Studies in the Social Sciences, 2008.
dc.relation Includes appendices.
dc.relation Includes appendices.
dc.subject.lcsh Phototherapy.
dc.title Anatomy of antidepressant effect of light: the role of the BNST lesions
dc.format.pages ix, 62 leaves;


Bu öğenin dosyaları

Bu öğe aşağıdaki koleksiyon(lar)da görünmektedir.

Basit öğe kaydını göster

Dijital Arşivde Ara


Göz at

Hesabım