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An information theoretical approach to functional connectivity in brain

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dc.contributor Graduate Program in Computer Engineering.
dc.contributor.advisor Bingöl, Haluk.
dc.contributor.advisor Akın, Ata.
dc.contributor.author Budur, Emrah.
dc.date.accessioned 2023-03-16T10:00:24Z
dc.date.available 2023-03-16T10:00:24Z
dc.date.issued 2011.
dc.identifier.other CMPE 2011 B87
dc.identifier.uri http://digitalarchive.boun.edu.tr/handle/123456789/12182
dc.description.abstract Mental disorders are usually associated with functional abnormalities of brain that are revealed by behavioral symptoms. Attention-deficit hyperactivity disorder (ADHD), in particular, is well known to be a common behavioral disorder with characteristic symptoms of inattentiveness, impulsivity and hyperactivity which impairs the life quality of the individuals. Although the characteristics of ADHD is well defined, the neurobiological reasons of this disorder is not fully discovered yet. The introduction of functional near infrared spectrocopy (fNIRS), which is a novel non-invasive optical imaging technology, provided an easy way to reveal hemodynamics of ADHD in brain. In this study, our aim was to find an information theoretical method to diagnose adults withADHDvia fNIRS.We assigned 10ADHDsubjects to experimental group and 12 control subjects to the control group. Each subject in experimental group is involved in two experimental runs which are executed when they are with and without medication denoted by ADHD-ON, ADHD-OFF, respectively. On the other hand, a single experimental run, which is denoted by CONT, is performed for the control group. The subjects performed the Stroop test in experiments. One-wayANOVAanalysis was conducted among three groups of data, namely ADHD-OFF, ADHD-ON and CONTROL, to compare the effect of MPH. Given the significance level of = 0:05, the result F = 6:86; p = 0:0036 indicates that the values of three groups differ significantly from each other. As a result, it is observed that medication normalizes the brain signals of the individuals in ADHD group towards healthy controls..
dc.format.extent 30cm.
dc.publisher Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2011.
dc.relation Includes appendices.
dc.relation Includes appendices.
dc.subject.lcsh Information storage and retrieval systems -- Medical care -- Evaluation.
dc.subject.lcsh Health facilities -- Administration -- Data processing.
dc.title An information theoretical approach to functional connectivity in brain
dc.format.pages xiv, 45 leaves ;


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