Pyramidal neurons are the most abundant excitatory cell type in cortex and hippocampus. The canonical topology of these glutamatergic neurons consists of a pyramidal-shaped soma, an apical dendrite extending vertically ...

Hippocampal region dysfunction is suggested to have an important effect for thecognitive impairments observed in Alzheimer̕s disease. In some patients, hippocampus andnearby structures show atrophy while other brain ...

Ceramide, besides its structural role in cell membrane as a sphingolipid, has essential roles in apoptosis, cell growth and di erentiation. In this study, the e ect of C2-ceramide (10 μM) application on whole cell currents ...

Parkinson’s disease is the second most common neurodegenerative disease both in Turkey and in the world. The studies show the effects of inflammatory mechanisms and reactive oxygen species in the neurodegenerative diseases. ...