Fındık, Hüseyin Doğa.
(Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2015., 2015.)
The objective of this thesis was to investigate the e ect of ligand binding on global vibrational modes of an enzyme, triosphosphate isomerase (TIM). For this aim, mixed coarse-grained elastic network model ENM (MCG ENM) ...