Browsing M.S. Theses by Title

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  • Fabrication of microfluidic devices for yeast culturing 
    Üçpınar, Sevda. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2016., 2016.)
    Microfluidic technology has appreciated extensive success in recent years. Microfluidics is a well understood physic domain and can be used to develop tools for a wide range of platforms comprising engineering, biological ...
  • Functional analysis of the genes in the glucose metabolic network by a system based modular approach 
    Yüzüak, Okan. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    In this study, all proteins associated with the Process Gene Ontology (GO) term “Glucose Metabolic Process” were collected and a network of all reported interactions among these entities was constructed with a stringent ...
  • Game theoric analysis of MAPK signaling pathways in Saccharomyces cerevisiae 
    Çavlı, Can. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2007., 2007.)
    Understanding cellular signaling is central for gaining insight into the molecular mechanisms behind diseases as well as adaptation of living cells to changes in the environment. Signaling pathways are often branched in ...
  • Gas chromatographic study of hydrocarbon adsorption on platinum/alumina catalyst 
    Yıldırım, Ramazan, 1962- (Thesis (M.S.)- Bogazici University. Institute for Graduate Studies in Science and Engineering, 1988., 1988.)
    The adsorption of three normal paraffins (n-pentane, n-hexane and n-heptane) and one isoparaffin (i-octane) on the commercial 0.3 %. wt PtJAI03 reforming catalyst were investigated using the elution (or the pulse) technique ...
  • Gas chromatographic study of hydrogen and hydrocarbon adsorption on platinum/alumina catalyst 
    Gönenç, Z. Sermin. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 1985., 1985.)
    The irreversible and the reversible adsorption of hydrogen on commercial 0.3%wt Pt/Aı2O3 reforming catalyst has been studied in a gas-solid chromatograph in the temperature range 74-233 °C and 96-237 °C respectively. The ...
  • Gating mechanism in nicotinic acetylcholine receptor channel 
    Karadağ, Serkan. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2006., 2006.)
    Nicotinic acetylcholine receptor (nAChR) is a ligand gated ion channel. Aberrations of nAChR is the primary reason of many congenital myasthenic syndromes. The mechanism behind the function of nAChRs is still unclear. In ...
  • Genome-scale metabolic reconstruction of cryptococcus neoformans and development of treatment strategies 
    Demirtaş, Mehmet Yiğit. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2021., 2021.)
    Cryptococcus neoformans is a common opportunistic human pathogen that causes fatal infections, especially for immunocompromised individuals. The computational systems biology approach enables the elucidation of the ...
  • Glucose avidase immobilization by polymer matricies in supercritical carbon dioxide environment for biosensor preparation 
    İnoğlu, Nilay. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2007., 2007.)
    In this study, immobilization of glucose oxidase (GOX) by polyurethane (PU) film and PU foam matrices using supercritical carbon dioxide (scCO2) was realized and proposed as a new technique to be used in biosensor preparations. ...
  • Growth of protein-rich micro-organisms in petroleum 
    Bilgin, Ömer. (Thesis (M.S.) - Robert College. Faculty of Graduate School of Engineering, 1967., 1967.)
  • Heat transfer coefficients for finned tubed coil immersed in agitated vessel 
    Kızılçeç, Fatma. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 1986., 1986.)
    Heat transfer coefficients for agitated liquids in a flat bottomed vessel equipped with finned tube helical coil were determined over the 125-500r.p.m range of agitator speeds by using a flat paddle turbine impeller in ...
  • Hinge prediction using elastic network models 
    Emekli, Uğur. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2006., 2006.)
    The motion and interaction of rigid parts in a protein connected by hingers are important for the function of the protein. This makes identification of the hinge region particularly important. In this work a method and web ...
  • How intrinsic dynamics and allostery in G-protein coupled receptors (GPCRS) define functional selectivity? 
    Duman, Özge. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2020., 2020.)
    G-protein Coupled Receptors (GPCRs) are the largest family of the of sensory proteins which play an important role in many diseases related to signaling pathways. Thus, understanding GPCR activation mechanism is a corner ...
  • Identification of allosteric AKT inhibitors by computational methods 
    Gürsoy Yılmaz, Oya. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2013., 2013.)
    AKT kinases are known to be major contributors to the development of many human cancers according to preclinical data and studies of tumor specimens. Design and development of small molecule inhibitors targeting AKT and ...
  • Identification of drug targets towards prostate canser 
    Esvap, Elif. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2018., 2018.)
    Prostate cancer (Pca) is one of the leading cause of cancer deaths and second common cancer type in men. Identifying novel diagnostics and drug targets specific for Pca is critical since early detection and treatment are ...
  • Identification of key transcription factors in glucose sensing pathway in Saccharomyces Cerevisiae 
    Alazi, Ebru. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2010., 2010.)
    In this study, a genome-scale transcriptional regulatory network (TRN) in S. cerevisiae was constructed and integrated with the transcriptome data available in literature for the mutants of the glucose signaling pathway ...
  • Identification of native conformations of proteins using a low resolution model 
    Özkan, Ş. Banu. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Sciences and Engineering, 1997., 1997.)
    Exhaustive enumeration is performed by using a low resolution model. The secondary structure elements of the proteins are kept as rigid blocks. Large ensembles of decoy structures are generated by rotating the virtual ...
  • Identification of perturbation-responsive key transcription factors in transcriptional regulatory networks 
    Kınıkoğlu, Fatma Beste. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2006., 2006.)
    In eukaryotic cells, most genes are found to be regulated by various temporary andpermanent transcription factors whose activity levels change as response to perturbations.Discovering the underlying mechanism of complex ...
  • Identification of PTP1B dynamics using frequency response analysis 
    Eren, Dilek. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    Protein tyrosine phosphatase 1B (PTP1B) plays a key role as negative regulator of insulin and leptin signaling. In human PTP1B, a significant conformation change is seen in the WPD loop from open (inactive) to closed ...
  • Identification of the relations between synthesis conditions and compressive strength in geopolymer systems via statistical learning methods 
    Köse, Kadriye Deniz. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2019., 2019.)
    Geopolymers are inorganic amorphous materials, which can be used in construction industry, and their production is characterized by low CO2 emission. Compressive strength (CS) is a durability measure, which, in the case ...
  • Identification of TPX inhibitors against pathogen-host interactions 
    Deniz, Utku. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2014., 2014.)
    Antibiotic resistance is a major health issue as due to the emergence of multidrug resistant bacteria. Thus, there is an increasing need for the identification of new drug targets and discovery of novel scaffolds in the ...

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