Browsing Ph.D. Theses by Title

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  • Linear and multi-arm functionalizable polymeric constructs for targeted drug delivery and imaging applications 
    Gök, Özgül. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2014., 2014.)
    Multifunctional polymers with different architectures were designed as macromolecular carriers for drug delivery and imaging applications. To this end, linear and multiarm copolymers incorporated with reactive groups were ...
  • Liposomes for encapsulating drugs and complexing DNA 
    Çağdaş, Fatma Melis. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2013., 2013.)
    Surface-active substances, amphiphiles, show the ability of self-organization in solvents, forming self-assemblies with a large variety of morphologically different structures. One of these structures is liposomes, formed ...
  • Modeling the selectivity in pericyclic reactions 
    Ölçüm, Nihan Çelebi. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2009., 2009.)
    Pericyclic reactions are very powerful and widely utilized transformations to obtain complex molecules. The selective versions have received remarkable interest and have found extensive use in synthetic organic chemistry ...
  • Modeling the selectivity, catalytic and binding effects in organic reactions and protein environment 
    Dedeoğlu, Burcu. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2015., 2015.)
    In this dissertation, quantum chemical tools, in particular density functional methods are used to address problems related with the selectivity, catalytic and binding effects in different fields of chemistry, such as ...
  • Modeling the solvent effect, kinetics, morphology and catalysis in polymerization reactions 
    Özaltın, Tuğba. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2016., 2016.)
    In this dissertation, quantum chemical tools, in particular density functional theory (DFT), molecular dynamics (MD) and coarse-grained (CG) simulations are used to address the solvent e ect, kinetics, morphology and ...
  • Molecular dynamics study of macromolecular motions and polypeptide helical stabilities in solution 
    Doruker, Pemra. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 1995., 1995.)
    Molecular dynamics simulations have been performed to investigate the relative importance of solvent effect and intramolecular conformational potentials on the properties of polymers in dilute solition. Bead-spring, ...
  • Molecular modeling of Bcl-xL post-translational modifications and of keteniminium salts 
    Tanrıver, Gamze. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2022., 2022)
    Computational chemistry plays an important role in deciphering the structural proper ties of systems by using different approaches, such as quantum mechanics (QM) and molecular mechanics (MM) and gives insight by mimicking ...
  • Multifunctional monomeric and polymeric photoinitiators for free radical photopolymerization 
    Gençoğlu, Türkan. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2022., 2022)
    In this study, novel polymerizable, polymeric and branched photoinitiators (PIs) were synthesized to attain high polymerization efficiency, migration stability, visible light absorption and water solubility to address ...
  • Novel functional hydrogels and polymer coated magnetic nanoparticles with degradable linkers for biomedical applications 
    Aydın, Duygu. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2017., 2017.)
    In this thesis, the design and fabrication of novel reactive interfaces such as hydrogels and polymer coated nanoparticles were investigated for applications related to the delivery of therapeutic agents. Randomly crosslinked ...
  • Polymeric tubes prepared from poly (vinyl alcohol) fiber templates 
    Çavuşoğlu, Jesmi. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2016., 2016.)
    In this study, the fabrication of covalently crosslinked polymeric tubes by using poly(vinyl alcohol) (PVA) fiber templates has been demonstrated. The crosslinking on the surface of PVA fiber templates was achieved by two ...
  • Polymerization reactions of functionalized vegetable oils with petroleum-based macromonomers 
    Öztürk, Cem. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2010., 2010.)
    The aim of this work is to synthesize new polymers from plant oils. Polymerization of plant oil triglycerides is possible by attaching a polymerizable group to the triglyceride. This strategy has been used by us and by ...
  • Preparation characterization and drug release behavior of thermo-and pH-responsive hydrogels and microspheres 
    Taşdelen, Dinçer Betül. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2002., 2002.)
    In the present work, N-isopropylacrylamide/itaconic acid and N-isopropylacrylamide /maleic acid copolymeric hydrogels were prepared by irradiating the ternary mixtures of Nisopl- opylacrylamide/diprotic acid moieties ...
  • Reactive and 'clickable' hydrophilic nanofibers as novel biomaterials 
    Kalaoğlu Altan, Özlem İpek. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2017., 2017.)
    Among many other nanomaterials, polymeric nanofibers have gained attraction in biomedical applications due to their unique properties such as high surface area, porosity and physical resemblance to the extracellular matrix. ...
  • Redox-responsive biodegradable polymeric materials for biomedical applications 
    Çalık, Filiz. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2022., 2022)
    In recent years, biodegradable and stimuli-responsive polymeric materials have gained importance in cancer research and biomedical applications. Such materials can be used as implants in the body and a nano-sized drug ...
  • Role of ionic liquids on the reactivity and selectivity of diels- alder reactions and single site catalysts 
    Akgül, Deniz. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2022., 2022)
    Ionic liquids (ILs) have gained interest because of their features such as high thermal stability, high chemical inertness, conductivity, their ability to dissolve organic and inorganic substances. It is possible to tune ...
  • Smart polymeric carriers :|targeted delivery of therapeutic agents 
    Karaçivi, Merve. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2019., 2019.)
    In cancer research, studies about polymer drug conjugates and targeted delivery of chemotherapy agents are gaining great attention due to their ability to enhance biodistribution profiles and improve efficacy of chemotherapy ...
  • Smart polymeric prodrugs for targeted drug delivery and functionalizable hydrogels for biosensing applications 
    Kağa, Sadık. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2016., 2016.)
    Biosensing applications have an enormous place for diagnosis of numerous diseases. New platforms and materials have been developed to detect markers for several diseases. However, well defined materials are required for ...
  • Stimuli responsive functional polymeric materials for biomedical applications 
    Demirer, Hatice Betül. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2019., 2019.)
    This work consists of synthesis, structural characterization and evaluation of stimuliresponsive functional polymers and hydrogels designed for biomedical applications. In the first project pH and redox responsive degradable ...
  • Synthesis and evaluation of novel phosphonated and bisphosphonated methacrylates with possible environmental and biomedical applications 
    Bilgici, Zeynep Saraylı. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2013., 2013.)
    In this study, a series of mostly alkyl α-hydroxymethacrylate (RHMA)-derived novel monomers in four groups, and polymers of some of them were synthesized for various purposes including dental, bone-targeting and metal-binding ...
  • Synthesis and reactions of thioureas, their cyclized derivatives and oxazolidindiones 
    Tunçel, Şenel Teke. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2019., 2019.)
    In this study, several single enantiomer thioureas were synthesized and converted to their cyclic derivatives: 2-imino-thiazolidin-4-ones and 5-benzylidene derivatives. The conformations of the thioureas were determined ...

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