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Konu "Retina." için Moleküler Biyoloji ve Genetik listeleme

Konu "Retina." için Moleküler Biyoloji ve Genetik listeleme

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  • ERK, AKT and PKA as regulatory kinases of SIK2 in FGF signaling in muller cells 
    Ejder, Funda. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2011., 2011.)
    FGF2 dependent retinal Müller cell proliferation is elicited mainly via activation of Ras/MAPK pathway. Phosphorylation/dephosphorylation of intermediates is one of the key mechanisms for the transient and rapid regulation ...
  • Identification of candidate substrates of SIK2 in vitro 
    Küser, Gamze. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2006., 2006.)
    SIK2 is a serine/threonine kinase widely expressed in rat retina and it is postulated to be a potential regulator of FGF signal transduction in retina. The aim of this work is to explore a link between SIK2 and FGF/ERK ...
  • SIK2 expression in retinal cells and its possible involvement along with PKA in FGF9 signal transduction 
    Özmen, Yeşim. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2006., 2006.)
    FGF signal transduction pathway activates a cascade of kinase and phosphatase dependent phosphorylation and dephosphorylation events. The pathway is subject to tight control mechanisms through negative feedback exerted by ...
  • SIK2 involvement in dowregulation of FGF signaling through Gab1 and Raf1 
    Sert, Yeliz Yılmaz. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2011., 2011.)
    Proliferative response of Müller cells to FGF2 is propagated via Ras/MAPK pathway, and involves rapid and transient ERK1/2 activation. Results from our laboratory implicate SIK2 in the regulation of FGF2 signaling via ...