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Browsing Moleküler Biyoloji ve Genetik by Title

Browsing Moleküler Biyoloji ve Genetik by Title

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  • Sınmaz, Merve Gizem. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2018., 2018.)
    Adipokinetic hormone (AKH) is an insect neuropeptide and known as gonadotropinreleasing hormone, which is orthologue to humans. It is released from corpora cardiaca and acts generally on fat body for energy mobilization. ...
  • Şeker, Tuncay. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2009., 2009.)
    β-catenin is a key component of Wnt pathway which plays an important role in tumorigenesis. In our previous study, candidate genes regulated byWnt/ β-catenin/TCF pathway were identified in hepatocellular carcinoma-derived ...
  • Mandacı, Barış Can. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2022., 2022)
    Intellectual Disability (ID) is a heterogenic neurodevelopmental disorder seen in different spectrums in affected individuals. Resulting problems in the diagnosis of ID and limitations in its treatment constitutes a great ...
  • Çavuşoğlu, Kader. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2007., 2007.)
    β-catenin, a cytoplasmic component of the Wnt signaling pathway, is observed to be aberrantly activated in several types of tumors, including hepatocellular carcinoma. The aim of this study is to identify novel genes that ...
  • Öztürk, Arzu. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2010., 2010.)
    The one receptor - one neuron rule is a common phenomenon observed in sensory organs. In the Drosophila eye, each photoreceptor expresses one of six different rhodopsin genes. The expression patterns of inner photoreceptors ...
  • Aslan, Tolga. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2022., 2022)
    G protein coupled receptors are a large family of cell surface receptors and are involved in a plethora of physiological functions from vision to various neuronal func tions. They have been a major target in the pharmaceutical ...
  • Yılmaz, Erdem. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2014., 2014.)
    IRF4 is a critical transcription factor in the development and function of immune cells, and additionally, it is deregulated in certain myeloid and lymphoid malignancies. Un-til recently, IRF4 expression was thought to be ...
  • Ayhan, Mustafa Can. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2013., 2013.)
    Interferon Regulatory Factor 4 (IRF4, also known as MUM1, LSIRF, NFEM5, and ICSAT) is a transcription factor with important regulatory roles on B-cell matura-tion and differentiation. Although the first identification of ...
  • Yalçınkaya, Mustafa. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2015., 2015.)
    NOD-like receptors (NLRs) are a family of cytoplasmic proteins with members regulating inflammation and apoptosis. NLRP13 is a novel PYRIN domain containing NLR family member and the roles of NLRP13 in these pathways is ...
  • Akiva, İzzet. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2016., 2016.)
    The Wnt/β-catenin signaling pathway is an evolutionary conserved pathway which has important functions in vertebrate early development such as axis formation, cellular proliferation and morphogenesis. The activation of ...
  • Kahraman, Ayşe. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2022., 2022)
    Characterized by deficits in both intellectual ability and adaptive behavior, intellectual disabilities (IDs) are one of the major neurodevelopmental disorders with a prevalence of 1- 3% worldwide. Development of Next ...
  • Çağlayan, Melike. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2010., 2010.)
    The DNA polymerase I genes of seven newly identified Geobacillus species within the family Bacillaceae, were cloned, sequenced and overexpressed in Escherichia coli. The polA gene of these species encodes DNA polymerase I ...
  • Tufan, Hale Ann. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2006., 2006.)
    Nearly half of the agricultural land in Turkey is devoted to wheat. Turkey is one of the leading durum wheat producers in the Middle East and one of the most important biotic stress factors restricting the production is ...
  • Tınaztepe, Emir. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2009., 2009.)
    Odorant receptors which partake in the detection of both water-soluble and airborne chemicals constitute the largest family of seven-transmembrane G-Protein-Coupled Receptors in the majority of vertebrates. Since their ...
  • Başdağ, Bilal. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2018., 2018.)
    Recycling of sugar-containing organic compounds (saccharides) have importance for metabolic activity, cellular growth, and differentiation. During this recycling process, many enzymes, primarily lysosomal enzymes, play a ...
  • Gültekin, Yetiş. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2011., 2011.)
    NOD like receptors recognize infection and cellular damage. They are characterized by an N terminal protein interaction domain, central oligomerization domain, termed nucleotide binding domain and leucine rich repeat domain ...
  • Çağlayan, Melike. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2005., 2005.)
    The DNA polymerase I gene of a recently described Geobacillus species, Geobacillus anatolicus from a terrestrial hydrothermal vent has been cloned and expressed in Escherichia coli. Evolutionarily conserved regions of DNA ...
  • Şahin, Toros. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2006., 2006.)
    Elongation factor EF-Ts from Geobacillus anatolicus was cloned, expressed and purifed as a His-tagged recombinant protein in Escherichia coli. The first step in this study was the determination of the nucleic acid sequence ...
  • Akalın, Barış. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2006., 2006.)
    In this study, elongation factor Tu (EF-Tu) from Geobacillus anatolicus was cloned, expressed and purifed as a His-tagged recombinant protein in Escherichia coli. At first, the nucleic acid sequence of Geobacillus anatolicus ...
  • Atasoy, Arif Murat. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2011., 2011.)
    Olfactory receptors constitute the largest G-Protein-Coupled Receptor family in humans and in other vertebrates. Olfactory receptor genes are expressed in the olfactory sensory neurons in the olfactory epithelia and are ...

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