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Yazar "Emre, Tolga." için Moleküler Biyoloji ve Genetik listeleme

Toplam kayıt 7, listelenen: 1-7

A novel tool for the identification of locus-specific chromatin proteins

Ogmen, Anna. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2019., 2019.)

Genomic DNA is maintained and regulated by chromatin proteins. Methods for research of chromatin organization are numerous and established, however, it is still a challenge to identify novel chromatin proteins associated ...
Development & application of novel methods to identify locus-specific transcriptional regulators

Selcen, İpek. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2019., 2019.)

Chromatin-associated factors play important roles in the regulation of gene expression. It is essential to identify these factors in order to elucidate their functional roles at the target sites. There are a number of ...
Genome-wide localisation analysis for IRF4 target gene identification in melanoma cell lines

Afshar, Ulduz Sobhi. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2015., 2015.)

Interferon Regulatory Factor 4 (IRF4) is a key transcription factor in development and function of immune cells. Also it has been shown that elevated IRF4 expression is a key factor for survival in some myeloid and lymphoid ...
Identification of interferon regulatory factor 4 (IRF4) - interacting proteins in melanoma cell lines

Erkan, Ekin Ece. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2015., 2015.)

IRF4 is a member of interferon regulatory factor family of transcription factors. Previously, IRF4 was shown to have regulatory roles in immune cells and B-cell malignancies. In addition, IRF4 was recently shown to be ...
Identification of the upstream regulators of interferon regulatory factor 4 (IRF4) expression in melanoma cells

Tufan, Ahmet Buğra. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2015., 2015.)

Melanoma is derived from melanin pigment producing cells which are known as melanocytes. Late stage, metastatic melanoma is considered as one of the most aggressive malignancies with one of the worst prognosis. IRF4 belongs ...
Implementation of CRISPR based techologies for genome and gene expression maniplation of IRF4 in melanoma cells

Yerinde, Cansu. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2016., 2016.)

Clustered Regularly Interspaced Short Palindromic Repeats, CRISPR/Cas9, which was originally characterized as an adaptive immune system in bacteria, has become the most powerful genome engineering technology in recent years ...
Investigation of IRF4-MEF2D protein-protein interaction in melanoma cells

Hedaya, Laila Samir Abed. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2021., 2021.)

Cancer is a leading cause of death worldwide. Protein-protein interactions (PPIs) constitute a fundamental unit of the oncogenic signaling pathways that stimulate survival, growth and proliferation of cancer cells. Therefore, ...

Yazar "Emre, Tolga." için Moleküler Biyoloji ve Genetik listeleme

Yazar "Emre, Tolga." için Moleküler Biyoloji ve Genetik listeleme

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