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Browsing Kimya Mühendisliği by Author "Sarıyar, Berna."

Browsing Kimya Mühendisliği by Author "Sarıyar, Berna."

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  • Bacterial uptake of antimicrobial peptides 
    Irvalı, Deniz. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2016., 2016.)
    The discovery of beta lactam antibiotics has been a groundbreaking improvement in the treatment of bacterial diseases. However, most bacteria have gained resistance against beta lactam antibiotics which rendered them ine ...
  • Beta-lactamase binding to blip and blip based peptides 
    Doğan, Aslıgül. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2011., 2011.)
    Extensive use of antimicrobial agents has generated selective pressure on bacteria and resulted in development of resistance to beta-lactam antibiotics. The main resistance mechanism of bacteria is the production of ...
  • Beta-lactamase ligand recognition 
    Menekşedağ, Deniz. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    Beta-lactamases hydrolyze the beta-lactam ring of antibiotics, rendering them ineffective. Understanding the inhibitor recognition mechanism of beta-lactamases will give important information toward the fight against ...
  • Drug design against antimicrobial resistance 
    Kalyon, Kevser Betül. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2016., 2016.)
    Cell penetrating peptides are extensively studied due to their potential for having antimicrobial properties. The purpose of this study is to understand the mechanisms of certain cell penetrating peptides in bacterial and ...
  • Effect of simultaneous beta-lactamase inhibitor protein expression on cellular beta-lactamase activity 
    Yalaz, Kadriye Simay. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    β-lactam antibiotics are commonly used in the treatment of bacterial infections. However, due to underuse and misuse of β-lactam antibiotics, bacteria have developed mechanisms that counteract β-lactam antibiotics. The ...
  • Investigation of in-vivo inhibition of β-lactamase by β-lactamase inhibitor protein 
    Akkaya, Ayşe Ezgi. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2010., 2010.)
    β-lactam antibiotics, which target transpeptidase enzymes that synthesize the bacterial cell wall, are the most widely utilized antimicrobial agents. However owing to the widespread usage, bacteria acquire resistance to ...
  • Tem-1 β-lactamase activity in the presence of blip in cellular environments 
    Ceylan, Celal. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2010., 2010.)
    β-lactams are an important class of antibiotics used in the treatment of various infections. These antibiotics are the most widely utilized by virtue of their high efficacy, low cost and safety profile. This widespread, ...
  • Understanding the membrane penetration of antimicrobial 
    Alaybeyoğlu, Begüm. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    The studies on β-lactam antibiotics have found great interest since the use of antimicrobial therapy became widespread and as a result, bacteria started to develop resistance against β-lactam antibiotics. The most effective ...

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