Arşiv ve Dokümantasyon Merkezi
Dijital Arşivi

Yazar "Ülgen, Kutlu Ö." için Kimya Mühendisliği listeleme

Yazar "Ülgen, Kutlu Ö." için Kimya Mühendisliği listeleme

Sırala: Sıra: Sonuçlar:

  • A droplet-based platform for high throughput screening of drug administered cells 
    Kasım, Müge. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2019., 2019.)
    Droplet-based microfluidic systems move forward since 2000s having benefits compared to the conventional methods like improved sensitivity, automated and high throughput operation. This thesis involves a combined approach ...
  • A microfluidic study on the regulation of ribosome biogenesis in saccharomyces cerevisiae 
    Yurdakul, Ekin. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2018., 2018.)
    Microfluidic bioreactors are economical, efficient and usable reactors for conducting biological studies aiming to observe cells under continuous flow. In the present work, microchips from COP (cyclo olefin copolymer) ...
  • A study on hdyrodynamics and heat transfer in a bubble column reactor 
    Kantarcı, Nigar. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2003., 2003.)
    A bubble column reactor was designed and the accessory equipments were fixed in order to carry out hydrodynamics and heat transfer measurements. The experiments were initiated with two-phase air-water system and extended ...
  • A study on protein and DNA analysis by Capillary electrophoresis 
    Özer, Asuman Nevra. (Thesis (M.S.)- Bogazici University. Institute for Graduate Studies in Science and Engineering, 1999., 1999.)
    The aim of this research was to establish a method for the analysis of several proteins and DNA using capillary electrophoresis. Bovine serum albumin, human serum proteins and some restriction enzymes namely Taq1, EcoR1, ...
  • Calcium signaling system in multiple species : structural and functional analyses of protein interaction networks 
    Tiveci, Senem. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2011., 2011.)
    Calcium is an important second messenger to have a key role in many processes occurring in the cell. Understanding the mechanisms of calcium signaling in multiple species i.e. yeast and worm may help to untangle calcium ...
  • Computational prediction of protein-protein interactions in sphingolipid signaling network 
    Güngörmez, Yasemen. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2010., 2010.)
    Proteins carry out most of the work in the cell such as immunological recognition, DNA repair and replication, enzymatic activity, cell signaling by interacting with other proteins. Therefore deciphering protein-protein ...
  • Design and fabrication of a microbioreactor for yeast culturing 
    Gençtürk, Elif. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2015., 2015.)
    From the beginning of the 1980, a new platform called “microfluidics” has been appeared. Microfluidics generally means the miniaturization of devices and systems, and this field covers engineering, biochemistry and ...
  • Development of microfluidic platforms for therapeutic purposes 
    Gençtürk, Elif. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2021., 2021.)
    This thesis describes the present state of the development and applications of microfluidic systems used in cell biology and analyses of experiments conducted with in house fabricated thermoplastic based microfluidic ...
  • Drug target identification in sphingolipid metabolisim against G. lamblia 
    Yavuztürk, Fatma Banu. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2009., 2009.)
    Sphingolipids are essential cell compounds, mostly found in membranes and participated in cell events such as cell signaling, proliferation and apoptosis. Sphingolipid biosynthesis pathways have recently been highlighted ...
  • Effects of nanocarriers of saccharomyces cerevisiae 
    Özbek, Özlem. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2019., 2019.)
    Nanocarriers have been studied widely owing to their promising features in the field of drug delivery and they improve pharmacokinetic properties, biodistribution, solubility and stability, provide controlled release and ...
  • Fabrication of microfluidic devices for yeast culturing 
    Üçpınar, Sevda. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2016., 2016.)
    Microfluidic technology has appreciated extensive success in recent years. Microfluidics is a well understood physic domain and can be used to develop tools for a wide range of platforms comprising engineering, biological ...
  • From yeast to human : unraveling sphingolipid metabolism through macroscopic and microscopic analyses 
    Kavun Özbayraktar, Fatma Betül. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2011., 2011.)
    Sphingolipids are both structural and regulatory components of the cell, where they control processes decisive in cell’s fate. The pharmacological manipulation of the sphingolipid metabolism in cancer therapeutics necessitates ...
  • Game theoric analysis of MAPK signaling pathways in Saccharomyces cerevisiae 
    Çavlı, Can. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2007., 2007.)
    Understanding cellular signaling is central for gaining insight into the molecular mechanisms behind diseases as well as adaptation of living cells to changes in the environment. Signaling pathways are often branched in ...
  • Genome-scale metabolic reconstruction of cryptococcus neoformans and development of treatment strategies 
    Demirtaş, Mehmet Yiğit. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2021., 2021.)
    Cryptococcus neoformans is a common opportunistic human pathogen that causes fatal infections, especially for immunocompromised individuals. The computational systems biology approach enables the elucidation of the ...
  • Identification of allosteric AKT inhibitors by computational methods 
    Gürsoy Yılmaz, Oya. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2013., 2013.)
    AKT kinases are known to be major contributors to the development of many human cancers according to preclinical data and studies of tumor specimens. Design and development of small molecule inhibitors targeting AKT and ...
  • Identification of drug targets towards prostate canser 
    Esvap, Elif. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2018., 2018.)
    Prostate cancer (Pca) is one of the leading cause of cancer deaths and second common cancer type in men. Identifying novel diagnostics and drug targets specific for Pca is critical since early detection and treatment are ...
  • Identification of TPX inhibitors against pathogen-host interactions 
    Deniz, Utku. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2014., 2014.)
    Antibiotic resistance is a major health issue as due to the emergence of multidrug resistant bacteria. Thus, there is an increasing need for the identification of new drug targets and discovery of novel scaffolds in the ...
  • In silico analysis of neutral sphingomyelinase 2 
    Yağcı, Zarife Begüm. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2018., 2018.)
    Neutral sphingomyelinase 2 (nSMase2) is an important sphingolipid metabolism enzyme that generates ceramide through the hydrolysis of sphingomyelin (SM) present in the plasma membrane. It has been suggested as a therapeutic ...
  • Integrated analysis of metabolome profiles and gene expression in respiratory deficient deletion mutants of Saccharomyces Cerevisiae 
    Pir, Pınar. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2005., 2005.)
    A study on transcriptional and metabolic response of S. cerevisiae cells toenvironmental and genetic perturbations was made. Deletion mutants with BY4743backgound were used. Homozygous deletion mutants ho/ho (reference ...
  • Integrated neurovascular coupling (NVC) model: an fNIRS study on migraine 
    Taşdöğen, Selin. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2007., 2007.)
    Functional imaging techniques play a major role in monitoring the changes in brain hemodynamics. Migraine is one of the weirdest illnesses that have ever been described. It does not leave any symptom in patients like the ...