Browsing Kimya Mühendisliği by Title

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  • Heat transfer coefficients for finned tubed coil immersed in agitated vessel 
    Kızılçeç, Fatma. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 1986., 1986.)
    Heat transfer coefficients for agitated liquids in a flat bottomed vessel equipped with finned tube helical coil were determined over the 125-500r.p.m range of agitator speeds by using a flat paddle turbine impeller in ...
  • Hinge prediction using elastic network models 
    Emekli, Uğur. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2006., 2006.)
    The motion and interaction of rigid parts in a protein connected by hingers are important for the function of the protein. This makes identification of the hinge region particularly important. In this work a method and web ...
  • How intrinsic dynamics and allostery in G-protein coupled receptors (GPCRS) define functional selectivity? 
    Duman, Özge. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2020., 2020.)
    G-protein Coupled Receptors (GPCRs) are the largest family of the of sensory proteins which play an important role in many diseases related to signaling pathways. Thus, understanding GPCR activation mechanism is a corner ...
  • Identification of allosteric AKT inhibitors by computational methods 
    Gürsoy Yılmaz, Oya. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2013., 2013.)
    AKT kinases are known to be major contributors to the development of many human cancers according to preclinical data and studies of tumor specimens. Design and development of small molecule inhibitors targeting AKT and ...
  • Identification of drug targets towards prostate canser 
    Esvap, Elif. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2018., 2018.)
    Prostate cancer (Pca) is one of the leading cause of cancer deaths and second common cancer type in men. Identifying novel diagnostics and drug targets specific for Pca is critical since early detection and treatment are ...
  • Identification of key transcription factors in glucose sensing pathway in Saccharomyces Cerevisiae 
    Alazi, Ebru. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2010., 2010.)
    In this study, a genome-scale transcriptional regulatory network (TRN) in S. cerevisiae was constructed and integrated with the transcriptome data available in literature for the mutants of the glucose signaling pathway ...
  • Identification of native conformations of proteins using a low resolution model 
    Özkan, Ş. Banu. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Sciences and Engineering, 1997., 1997.)
    Exhaustive enumeration is performed by using a low resolution model. The secondary structure elements of the proteins are kept as rigid blocks. Large ensembles of decoy structures are generated by rotating the virtual ...
  • Identification of perturbation-responsive key transcription factors in transcriptional regulatory networks 
    Kınıkoğlu, Fatma Beste. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2006., 2006.)
    In eukaryotic cells, most genes are found to be regulated by various temporary andpermanent transcription factors whose activity levels change as response to perturbations.Discovering the underlying mechanism of complex ...
  • Identification of PTP1B dynamics using frequency response analysis 
    Eren, Dilek. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    Protein tyrosine phosphatase 1B (PTP1B) plays a key role as negative regulator of insulin and leptin signaling. In human PTP1B, a significant conformation change is seen in the WPD loop from open (inactive) to closed ...
  • Identification of the relations between synthesis conditions and compressive strength in geopolymer systems via statistical learning methods 
    Köse, Kadriye Deniz. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2019., 2019.)
    Geopolymers are inorganic amorphous materials, which can be used in construction industry, and their production is characterized by low CO2 emission. Compressive strength (CS) is a durability measure, which, in the case ...
  • Identification of TPX inhibitors against pathogen-host interactions 
    Deniz, Utku. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2014., 2014.)
    Antibiotic resistance is a major health issue as due to the emergence of multidrug resistant bacteria. Thus, there is an increasing need for the identification of new drug targets and discovery of novel scaffolds in the ...
  • In silico analysis of neutral sphingomyelinase 2 
    Yağcı, Zarife Begüm. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2018., 2018.)
    Neutral sphingomyelinase 2 (nSMase2) is an important sphingolipid metabolism enzyme that generates ceramide through the hydrolysis of sphingomyelin (SM) present in the plasma membrane. It has been suggested as a therapeutic ...
  • In silico determination of protein complexes in yeast 
    Karabıyık, Hilal Candan. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2008., 2008.)
    In this thesis, the protein complexes in an interaction network of 20,487 interactions between 4,944 proteins were determined by the integration of different biological datasets. We recruit different data sources that ...
  • Integrated analysis of drug resistance in Saccharomyces Cerevisiae identification of key transcription factors involved in drug resistance 
    Öç, Şebnem. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2011., 2011.)
    In this study, the transcriptome data from the three homozygous deletion mutants, Δqdr3/Δqdr3, Δpdr3/ Δpdr3, and Δho/Δho, of Saccharomyces cerevisiae grown in glucose or ammonium limited continuous cultures were investigated ...
  • Integrated analysis of metabolome profiles and gene expression in respiratory deficient deletion mutants of Saccharomyces Cerevisiae 
    Pir, Pınar. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2005., 2005.)
    A study on transcriptional and metabolic response of S. cerevisiae cells toenvironmental and genetic perturbations was made. Deletion mutants with BY4743backgound were used. Homozygous deletion mutants ho/ho (reference ...
  • Integrated neurovascular coupling (NVC) model: an fNIRS study on migraine 
    Taşdöğen, Selin. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2007., 2007.)
    Functional imaging techniques play a major role in monitoring the changes in brain hemodynamics. Migraine is one of the weirdest illnesses that have ever been described. It does not leave any symptom in patients like the ...
  • Integration of interactome and transcriptome data to reveal glucose repression pathway in Saccharomyces Cerevisiae 
    Hasdemir, Dicle. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2008., 2008.)
    Due to glucose’s role as a primary signaling molecule, a change in glucose level immediately stimulates certain elements of the glucose sensing and signaling pathway. This stimulation of the pathway activates the associated ...
  • Intensified dimethyl ether production from synthesis gas with CO2 
    Öztürk, Nusret Furkan. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2019., 2019.)
    Catalytic conversion of syngas to dimethyl ether (DME) is modeled in a mi crochannel reactor comprised of horizontal groups of rectangular shaped cooling and catalyst washcoated reaction channels involving counter–current ...
  • Interaction between CO and PtSn alloy: a theoretical study on understanding selective CO oxidation 
    Duru, Birim. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2008., 2008.)
    The adsorption properties of CO on PtSn(110) surface were investigated via quantum mechanical calculations. The adsorption energies and the geometries of CO molecule for all possible adsorption sites were calculated. The ...
  • Investigation of aging (chronological life span) in S. Cerevisiae by systems biology approaches 
    Yücel, Esra Börklü. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Social Sciences, 2013., 2013.)
    One of the major goals of biological systems research is to improve the human condition and quality of life. Aging is probably the most peculiar phenomenon that a cell, tissue and even an organism experiences. Although it ...

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