Browsing Kimya Mühendisliği by Title

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  • Identification of PTP1B dynamics using frequency response analysis 
    Eren, Dilek. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    Protein tyrosine phosphatase 1B (PTP1B) plays a key role as negative regulator of insulin and leptin signaling. In human PTP1B, a significant conformation change is seen in the WPD loop from open (inactive) to closed ...
  • Identification of the relations between synthesis conditions and compressive strength in geopolymer systems via statistical learning methods 
    Köse, Kadriye Deniz. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2019., 2019.)
    Geopolymers are inorganic amorphous materials, which can be used in construction industry, and their production is characterized by low CO2 emission. Compressive strength (CS) is a durability measure, which, in the case ...
  • Identification of TPX inhibitors against pathogen-host interactions 
    Deniz, Utku. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2014., 2014.)
    Antibiotic resistance is a major health issue as due to the emergence of multidrug resistant bacteria. Thus, there is an increasing need for the identification of new drug targets and discovery of novel scaffolds in the ...
  • In silico analysis of neutral sphingomyelinase 2 
    Yağcı, Zarife Begüm. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2018., 2018.)
    Neutral sphingomyelinase 2 (nSMase2) is an important sphingolipid metabolism enzyme that generates ceramide through the hydrolysis of sphingomyelin (SM) present in the plasma membrane. It has been suggested as a therapeutic ...
  • In silico determination of protein complexes in yeast 
    Karabıyık, Hilal Candan. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2008., 2008.)
    In this thesis, the protein complexes in an interaction network of 20,487 interactions between 4,944 proteins were determined by the integration of different biological datasets. We recruit different data sources that ...
  • Integrated analysis of drug resistance in Saccharomyces Cerevisiae identification of key transcription factors involved in drug resistance 
    Öç, Şebnem. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2011., 2011.)
    In this study, the transcriptome data from the three homozygous deletion mutants, Δqdr3/Δqdr3, Δpdr3/ Δpdr3, and Δho/Δho, of Saccharomyces cerevisiae grown in glucose or ammonium limited continuous cultures were investigated ...
  • Integrated analysis of metabolome profiles and gene expression in respiratory deficient deletion mutants of Saccharomyces Cerevisiae 
    Pir, Pınar. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2005., 2005.)
    A study on transcriptional and metabolic response of S. cerevisiae cells toenvironmental and genetic perturbations was made. Deletion mutants with BY4743backgound were used. Homozygous deletion mutants ho/ho (reference ...
  • Integrated neurovascular coupling (NVC) model: an fNIRS study on migraine 
    Taşdöğen, Selin. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2007., 2007.)
    Functional imaging techniques play a major role in monitoring the changes in brain hemodynamics. Migraine is one of the weirdest illnesses that have ever been described. It does not leave any symptom in patients like the ...
  • Integration of interactome and transcriptome data to reveal glucose repression pathway in Saccharomyces Cerevisiae 
    Hasdemir, Dicle. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2008., 2008.)
    Due to glucose’s role as a primary signaling molecule, a change in glucose level immediately stimulates certain elements of the glucose sensing and signaling pathway. This stimulation of the pathway activates the associated ...
  • Intensified dimethyl ether production from synthesis gas with CO2 
    Öztürk, Nusret Furkan. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2019., 2019.)
    Catalytic conversion of syngas to dimethyl ether (DME) is modeled in a mi crochannel reactor comprised of horizontal groups of rectangular shaped cooling and catalyst washcoated reaction channels involving counter–current ...
  • Interaction between CO and PtSn alloy: a theoretical study on understanding selective CO oxidation 
    Duru, Birim. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2008., 2008.)
    The adsorption properties of CO on PtSn(110) surface were investigated via quantum mechanical calculations. The adsorption energies and the geometries of CO molecule for all possible adsorption sites were calculated. The ...
  • Investigation of aging (chronological life span) in S. Cerevisiae by systems biology approaches 
    Yücel, Esra Börklü. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Social Sciences, 2013., 2013.)
    One of the major goals of biological systems research is to improve the human condition and quality of life. Aging is probably the most peculiar phenomenon that a cell, tissue and even an organism experiences. Although it ...
  • Investigation of bacterial infection strategies through bacteria-human protein-protein interactions by bioinformatics approaches 
    Gürses, Büşra. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2014., 2014.)
    Infectious diseases, which have been a serious threat for human life in ancient times, is still leading the causes of death and disability worldwide. Pathogens (viruses, bacteria, protozoa, fungi, etc.) express a wide range ...
  • Investigation of beta-lactamase ligand binding in vivo and in silico 
    Kanlıkılıçer, Pınar. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2009., 2009.)
    β-lactam antibiotics are the most commonly used antibiotics due to their high effectiveness, low cost, ease of delivery and minimal side effects. Bacteria have acquired resistance to these antibiotics. One of the mechanisms ...
  • Investigation of cell cycle network of yeast using lab-on-a-chip platform 
    Odabaşı, İrem Ezgi. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2017., 2017.)
    Genome instability has long been implicated as a salient causal factor in aging and age related diseases such as cancer and neurodegeneration. However, the molecular mechanisms associated with genome instability remain ...
  • Investigation of CO hydrogenation catalysts for direct synthesis of dimethyl ether 
    Ekmen, Çiğdem. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2014., 2014.)
    The aim of this work was to prepare and test bi-functional direct DME synthesis catalysts, including commercial ones, involving methanol synthesis and methanol dehydration functions. Catalyst beds were prepared by physical ...
  • Investigation of CO hydrogenation catalysts for producing oxygenated hydrocarbons 
    Kabakçı, Didem Büşra. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2014., 2014.)
    The objective of this study was to test the performance of promoted rhodium catalysts supported on silica for oxygenated hydrocarbon (particularly ethanol) production by CO hydrogenation. Two different catalysts were ...
  • Investigation of CO oxidation kinetics over gold catalysts 
    Ülgüel, Caner. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2011., 2011.)
    This experimental study involves preliminary work conducted over 0.5wt%Au/Al2O3 and kinetic study of low-temperature CO oxidation over 1wt%Au/1.25-wt%MgO/Al2O3 prepared by the homogeneous deposition-precipitation method. ...
  • Investigation of conformational fluctuations in protein dynamics: torsional Gaussian Network Model 
    Özbakır, Harun Ferit. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    Elastic network models based on Normal Mode Analysis (NMA) are very useful in determining the conformational fluctuations that would affect the functions of proteins. Gaussian Network Model (GNM) is proved to be a very ...
  • Investigation of coupling between collective dynamics and function of enzymes 
    Kocaman, Duygu. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2011., 2011.)
    To bridge the structure and function of an enzyme through dynamics is an important problem in protein science. For this aim, the vibrational dynamics for a set of enzymes with different biological units and fold types are ...

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