Browsing Kimya by Author "Monard, Gérald."

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Elucidation of the deamidation mechanism of asparaginyl residues in peptides and proteins

Çatak, Şaron. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2008., 2008.)

Demidation of proteins is a topic of wide interest that has been subject to experimental and theoretical studies. Deamidation is a nonenzymatic and spontaneous process that converta asparagine conformational changes in ...
Investigation of the deamidation reaction in the enzyme triosephosphate isomerase by means of computational chemistry tools

Uğur, İlke. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2014., 2014.)

Deamidation is the posttranslational modi cation of asparagine (Asn) and glutamine (Gln) residues, which is observed in several proteins and peptides. It has been shown that deamidation limits the lifetime of these ...
Molecular modeling of Bcl-xL post-translational modifications and of keteniminium salts

Tanrıver, Gamze. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2022., 2022)

Computational chemistry plays an important role in deciphering the structural proper ties of systems by using different approaches, such as quantum mechanics (QM) and molecular mechanics (MM) and gives insight by mimicking ...

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