Browsing Kimya by Author "Sanyal, Rana."

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  • Active and passive tumor targeting via micellar dendritic constructs 
    Sümer, Burcu. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2017., 2017.)
    Among many other nanotherapeutics, polymeric micellar systems are emerging as a very important class of nano-pharmaceuticals due to their ability to improve pharmacokinetics and bio-distribution of chemotherapy drugs as ...
  • Anti-angiogenesis chemotherapy agents 
    Çıtak, Duygu. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2010., 2010.)
    Angiogenesis can be explained as the growth of new blood vessels from pre-existing vasculature. It has an important and vital role in growth and development, as well as in wound healing. Anti-angiogenic substances suppress ...
  • Antibody-drug-conjugates as targeted chemotherapy agents for breast cancer 
    Gür, Salli. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2019., 2019.)
    Antibodies are large molecular weight proteins produced by the immune system. They have high affinity to receptors on different cells’ surfaces. Using this affinity, a number of studies have been conducted to deliver ...
  • Bone targeted photodynamic therapy 
    Demirci, Gönül. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2010., 2010.)
    Photodynamic therapy (PDT) is a method for treatment of cancerous tumors and many other diseases. PDT is the preferential delivery of a photosensitizer (PS) to tumor tissue which is followed by irradiation of light of ...
  • Core crosslinked polymeric micelles from dendritic macromolecules as drug delivery agents 
    Eceoğlu, Melike. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    Due to their biocompatibility and high loading capacity, polymeric micelles have received a lot of attention as efficient nanocarriers for drug delivery systems in recent years. Micelles from amphiphilic copolymers can be ...
  • Core reactive biodegradable multiarm star polymers 
    Kılıç, Elif. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2011., 2011.)
    Functionalizable macromolecules have attracted increasing attention as polymeric materials due to their wide application in material and biological sciences. Although a lot of work has been done in this area, little attention ...
  • Dendrimer assembly via non-covalent interactions 
    Karayel, Ali Hikmet. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2009., 2009.)
    Dendrimers are monodisperse and highly branched macromolecules which are built around a core. The segments that combine to form a dendrimer are called dendrons. The synthesis of dendrimers can be undertaken in a manner ...
  • Dendron-polymer-dendron based micelles as drug delivery systems 
    Manavoğlu, Emine Ece. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2011., 2011.)
    Polymeric micelles are known to be good candidates for drug release systems due to their high loading capacities of inner hydrophobic core as well as unique compatibility in the body. Micelles from amphiphilic copolymers ...
  • Design and synthesis of maleimide-containing biofunctionalizable nanofibers 
    Kıraç Aydın, Azize. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2017., 2017.)
    Polymeric nanofibers have gained great attention lately due to their unique properties, which makes them attractive candidates for usage in many applications. These properties include high surface area, porosity, encapsulation ...
  • Drug delivery platform for targeting osteosarcoma 
    Güler, Ülkü. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2017., 2017.)
    Drug delivery systems remain a challenge in the management of cancer and wide variety of diseases. Polymers containing different functional groups are widely used in the delivery of drugs. The molecular weight of the polymer ...
  • Drug encapsulated polymeric nanoparticles for targeting cancer cells 
    Genç, Sesil. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2015., 2015.)
    Targeted drug delivery systems have gained much attention in recent years due to the fact that it offers useful solutions to the problems concerning chemotherapy drugs. The main aim in targeted drug delivery is to transport ...
  • Effect of hydrophilic segment length on size and stability of core crosslinked micelles 
    Arslan, Rabia Kolat. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2014., 2014.)
    Polymeric micelles are being extensively studied in recent years for their potential use as drug carriers. They consist of hydrophilic and hydrophobic segments and due to the solubility difference between these segments, ...
  • Fabrication and functionalization of reactive polymeric coatings for biomedical applications 
    Gevrek, Tuğçe Nihal. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2017., 2017.)
    The work in this thesis describes the design and synthesis of novel reactive polymeric coatings that can be utilized for fabrication of functional interfaces for applications like biosensing and protective antibacterial ...
  • Functional macromolecular platforms: hydrogel and soluble polymer-based materials for biomedical applications 
    Arslan, Mehmet. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2015., 2015.)
    Design, fabrication and applications of novel hydrogel and soluble polymer-based macromolecular platforms employing functional polymer building blocks are described. Several click chemistry-based transformations and ...
  • Investigation of antibody-dye conjugates 
    Özer, Enfal. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2019., 2019.)
    Polymeric architectures are widely used in polymer therapeutics for both imaging and drug delivery applications. Design of these polymer drug conjugates consists of three parts: water soluble monomer, linker and the drug ...
  • Linear and multi-arm functionalizable polymeric constructs for targeted drug delivery and imaging applications 
    Gök, Özgül. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2014., 2014.)
    Multifunctional polymers with different architectures were designed as macromolecular carriers for drug delivery and imaging applications. To this end, linear and multiarm copolymers incorporated with reactive groups were ...
  • Micellar dendritic structures as drug delivery agents 
    Böke, Nazlı. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2013., 2013.)
    Among various polymeric systems, amphiphilic block copolymers with stimuli-responsive moities provide significant advantages in drug delivery systems due to their unique self assembly properties which provide interiors ...
  • Micellar drug delivery platform from diblock copolymers 
    Kavak, Nehir. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2019., 2019.)
    The main role of chemotherapeutic agents is killing the fast growing cells. Thus, they damage fast growing helathy cells like bone marrow as well. This harm can be prevented by modifying the existing chemotherapeutic agents ...
  • Novel dendron-polymer conjugates for drug delivery 
    Gök, Özgül. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2010., 2010.)
    Multi-armed macromolecules have attracted increasing attention as polymeric scaffolds for biological applications. One of the significant ways to improve the properties of these architectures is the incorporation of ...
  • Novel functional hydrogels and polymer coated magnetic nanoparticles with degradable linkers for biomedical applications 
    Aydın, Duygu. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2017., 2017.)
    In this thesis, the design and fabrication of novel reactive interfaces such as hydrogels and polymer coated nanoparticles were investigated for applications related to the delivery of therapeutic agents. Randomly crosslinked ...

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