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  • A study on halloysite reinforced chitosan hydrogel nanocomposites: synthesis, characterization & DYE adsorption properties 
    Palantöken, Sinem. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2015., 2015.)
    In this project, synthesis and characterization of a series of natural silica nanotube reinforced chitosan nanocomposite hydrogels are done. Nanocomposite hydrogels were prepared through physical crosslinking of chitosan ...
  • A theoretical investigation of solvent effect on the conformational equilibria of 2-substituted cyclohexanone ketal derivatives 
    Sağ-Erdem, Safiye. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 1995., 1995.)
    The conformational equilibria of 6-substituted-1,4-dioxospiro-[4.5]decanes and 7substituted-1,5-dioxospiro [5.5]undecanes, relatively complex polar systems, with substituents X=-CH3, -F, -CI, -CN, -OH, -OCH3, -N02 have ...
  • Active and passive tumor targeting via micellar dendritic constructs 
    Sümer, Burcu. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2017., 2017.)
    Among many other nanotherapeutics, polymeric micellar systems are emerging as a very important class of nano-pharmaceuticals due to their ability to improve pharmacokinetics and bio-distribution of chemotherapy drugs as ...
  • Activity of topotecan as topoisomerase IB inhibitor 
    Bali, Semiha Kevser. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2018., 2018.)
    Human Topoisomerase I (TopoI) is an enzyme that relaxes the supercoils on the DNA. First, it creates a nick only on one strand of DNA by covalently binding to it, and relaxes DNA by rotating the nicked strand around the ...
  • Adsorption of branched polymer chains onto solid substrates 
    Özer, Sümeyye. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2019., 2019.)
    Polymer thin films have a wide range of applications in photovoltaic materials, biomedical coatings, and nanolithography. Thin films are prepared using either solution or melt deposition techniques in which residual stresses ...
  • Aldol reactions of conformationally stable o-CF3 phenyl bearing axially chiral thiohydantoins 
    Bacak Erdik, Melis. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2021., 2021.)
    Novel axially chiral thiohydantoin derivatives bearing an o-CF3 phenyl ring have been synthesized atroposelectively from the reaction of R and S alanine, phenyl alanine and valine methyl ester HCl salts with ortho-triflu ...
  • An investigation of the carbon-carbon bond rupture in fluoroethanes by RRKM theory 
    Aviyente, Viktorya. (Thesis (Ph.D.)- Bogazici University. Institute for Graduate Studies in Social Sciences, 1983., 1983.)
    In this dissertation, the thermal decompositions of ethane, 1,1,2,2-tetrafl uoroethane, pentafl uoroethane and hexafl uoroethane have been subjected to a theoretical treatment i n terms of the quantum statistical RRKM ...
  • An investigation of the effect of CD, HG and ZN on the growth of two species of blue green algae 
    Ağlarca, Zeynep. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 1983., 1983.)
    In this research, effects of three metals, cadmium, mercury and zinc were investigated on two species of blue green algae, Anabaena flos aquae and Gloeocapsa. Cells were grown in sterile medium free of combined nitrogen ...
  • Analysis of the radical polymerizability of diallyl monomers 
    Tüzün, Nurcan Şenyurt. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2002., 2002.)
    In this study, the radical cyclopolymerization mechanism of diallylamine and diallyl ether monomers and their derivatives has been investigated by computational modeling. The calculations were performed by the Density ...
  • Anti-angiogenesis chemotherapy agents 
    Çıtak, Duygu. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2010., 2010.)
    Angiogenesis can be explained as the growth of new blood vessels from pre-existing vasculature. It has an important and vital role in growth and development, as well as in wound healing. Anti-angiogenic substances suppress ...
  • Antibody-drug-conjugates as targeted chemotherapy agents for breast cancer 
    Gür, Salli. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2019., 2019.)
    Antibodies are large molecular weight proteins produced by the immune system. They have high affinity to receptors on different cells’ surfaces. Using this affinity, a number of studies have been conducted to deliver ...
  • Aromatic carboxamides as non-steroidal inhibitors of CYP17 for the treatment of prostate cancer 
    Köseoğlu, Ahmet. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2015., 2015.)
    Cancer is the most common neoplasm of the prostate in developed countries. Since up to 80 % of Prostate Cancer (PCa) proliferation depends on androgens, most patients take hormone therapy as first choice of treatment. The ...
  • Assessing protein - ligand binding modes, novel drug skeleton candidates for PDE4B and conformational rearrangements of EF-TU in GTP hydrolysis with computational tools 
    Çifci, Gülşah. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2017., 2017.)
    In the first part of this dissertation, computer-aided drug design approaches, structurebased methodologies such as docking, molecular dynamics simulations and Gibbs free energy calculations with Molecular Mechanics-Generalized ...
  • Asymmetric syntheses, ring opening and stereoselective reactions, absolute conformation and activation barrier determinations on axially chiral oxazolidine derivatives 
    Ordu, Öznur Demir. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2008., 2008.)
    In this study, sterically hindered 5-methyl-3-(o-aryl)-2,4-oxazolidinediones, 5-methyl- 3-(o-iodophenyl)-2-thioxo-4-oxazolidinedione and 5,5-dimethyl-3-(o-aryl)-2,4- oxazolidinediones have been synthesized. Diastereomeric ...
  • Atroposelective synthesis and reactions of axially chiral thiohydantoins 
    Sarıgül, Sevgi. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2017., 2017.)
    Nonracemic axially chiral thiohydantoins were synthesized atroposelectively by the reaction of ortho-arylisothiocyanates with amino acid ester salts in the presence of triethylamine (TEA). However, the synthesis of the ...
  • Axialy chiral n-(o-aryl)-2-thioxo-oxazolidine-4-one and rhodanine derivatives: enantiomeric separation and determination of racemization barriers 
    Yılmaz, Esra Müjde. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2008., 2008.)
    In this study, sterically hindered 5,5-dimethyl-3-(o-aryl)-2-thioxo-4-oxazolidinones, 5,5-dimethyl-3-(o-aryl)-2-thioxo-4-thiazolidinones and 3-(o-aryl)-2-thioxo-4- thiazolidinones(rhodanines) have been synthesized as ...
  • Barriers to enantiomerization of 1-(o-ARYL) barbituric and -2-thiobarbituric acid derivaties 
    Oğuz, Semin Funda. (Thesis (Ph.D.) - Bogazici University. Institue for Graduate Studies in Science and Engineering, 2002., 2002.)
    In this study, 5,5-dimethyl-1-(0-aryl)barbituricI, 1-(0-ary1)barbituric and 1-(0-aryi)- 2-thiobarbituric acids have been synthesized by the reaction of the o-arylureas or the oaryl- 2-thioureas with the diethylmalonate or ...
  • Benchmarking TADF activity of sulfone based compounds 
    Hepgüler, Aslıhan. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2022., 2022)
    Thermally activated delayed fluorescence (TADF) mechanism can be explained as transfer of excitons from the first triplet excited state (T1) to the first singlet ex cited state (S1) by reverse intersystem crossing (RISC). ...
  • (BIS) phosphonate functionalized polymeric materials for biomedical applications 
    Altuncu, Merve Seçkin. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2022., 2022)
    This work describes synthesis, characterization, and evaluation of (bis)phosphonate functionalized monomers, macromers and crosslinkers as well as their polymers and crosslinked networks for biomedical applications such ...
  • Bone targeted photodynamic therapy 
    Demirci, Gönül. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2010., 2010.)
    Photodynamic therapy (PDT) is a method for treatment of cancerous tumors and many other diseases. PDT is the preferential delivery of a photosensitizer (PS) to tumor tissue which is followed by irradiation of light of ...

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