Fen Bilimleri Enstitüsü: Recent submissions

  • Aslan, Tolga. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2022., 2022)
    G protein coupled receptors are a large family of cell surface receptors and are involved in a plethora of physiological functions from vision to various neuronal func tions. They have been a major target in the pharmaceutical ...
  • Ergünay, Tunahan. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2022., 2022)
    Small Ubiquitin-like modifier (SUMO) is an essential eukaryotic post-translational modification. SUMO isoforms attach to specific lysine residues on target substrates to modi-fy their function, activity, solubility and ...
  • Ergün, Ebru Zeynep. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2022., 2022)
    Killer-cell immunoglobulin-like receptors (KIRs) are among the most prominent receptors regulating NK cell development and function. Most KIR ligands are the MHC class I molecules found on target cells. KIRs are responsible ...
  • Karahan, Zeynep Sena. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2022., 2022)
    Antigen-specific cancer immunotherapy has been developing since the 1990s and showing promising results. T cell receptors (TCR) and Chimeric antigen receptors (CAR) are the most commonly used tools for modifying T cells ...
  • Kartal, Özlem. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2022., 2022)
    Mitochondrial respiratory chain defects are the primary cause of mitochondrial disorders. Mitochondria have developed various adaptive responses to counteract the effects of these defects. In this study, the heart- and ...
  • Dokuzluoğlu, Zeynep. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2022., 2022)
    The zebrafish olfactory epithelium (OE) is a neuroepithelium that is able to re generate neurons. The ability of the OE for neuron regeneration stems from the pres ence of a dual progenitor system that persists to the ...
  • Güler, Kardelen. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2022., 2022)
    The peripheral olfactory epithelium (OE) is an exception to the limited capacity of the adult nervous system to undergo neurogenesis, which supports structural repair in response to traumatic injury. It continuously and ...
  • Çıracı, Sevgi. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2022., 2022)
    The NOD-like receptors (NLRs) are mainly known for their roles in inflamma tory responses and host defense against microbial pathogens, but they are also asso ciated with metabolic disorders, autophagy regulation, transcription ...
  • Mandacı, Barış Can. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2022., 2022)
    Intellectual Disability (ID) is a heterogenic neurodevelopmental disorder seen in different spectrums in affected individuals. Resulting problems in the diagnosis of ID and limitations in its treatment constitutes a great ...
  • Kahveci, Kübra. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2022., 2022)
    G-protein coupled receptors (GPCRs) are cell surface receptors that are consisted of seven-transmembrane α helices. Drugs targeting GPCRs account for one-third of clinically approved drugs; since many drugs target the ...
  • Denizli, İrem. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2022., 2022)
    Ochratoxin A (OTA), a secondary metabolite produced by especially Aspergillus and Penicillium species, is found as a contaminant in foods such as daily consumed corn flakes, coffee, meat and dairy products. OTA is a potential ...
  • Alkiraz, Aysu Şevval. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2022., 2022)
    The zebrafish olfactory epithelium (OE) has an exceptional neurogenic capacity, which supports the continuous turnover olfactory sensory neurons (OSNs) and efficient regeneration after injury. These processes depend on the ...
  • Kahraman, Ayşe. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2022., 2022)
    Characterized by deficits in both intellectual ability and adaptive behavior, intellectual disabilities (IDs) are one of the major neurodevelopmental disorders with a prevalence of 1- 3% worldwide. Development of Next ...
  • Pekbilir, Emre. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2022., 2022)
    The manifestation of Human Immunodeficiency Virus type 1 (HIV-1) infection is acquired immunodeficiency syndrome (AIDS), one of the major health problems worldwide. From the first step of infection to the end, HIV-1 ...
  • Yılmaz, Mehmet. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2022., 2022)
    Mitochondria provide a significant portion of the ATP to cells and govern cellu lar energy economics on ever-changing cellular energy requirements. Cells evolved to monitor mitochondrial stress and developed counteracting ...
  • Başakoğlu, Engin. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2022., 2022)
    This thesis discusses the smoothing properties of dispersive partial differential equations. In the first part of the thesis, we consider the Davey–Stewartson system on R 2 and demonstrate that the nonlinear part of the ...
  • Muslumov, Ruslan. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2022., 2022)
    Let G and H be finite groups and k be a commutative unitary ring. The Burnside group B(G,H) is the Grothendieck group of the category of finite (G,H)-bisets. The biset category kC of finite groups is the category defined ...
  • Keçkin, Murat. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2022., 2022)
    In 1959, Kadison and Singer asked whether every pure state of the diagonal subspace D(ℓ2) of B(ℓ2) has a unique pure state extension to B(ℓ2). This problem has remained open until 2013; in 2013 it has been solved by a team ...
  • Üze, Berkan. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2022., 2022)
    The theory of motives was originally conceived by Alexander Grothendieck as a universal cohomology theory for algebraic varieties. In the decades since it was first introduced, it has become a vast and profoundly sophisticated ...
  • Değirmenci, Pınar. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2022., 2022)
    Determining whether the ring of integers OK of an algebraic number field K of degree n admits a power integral basis is one of the classic problems in algebraic number theory. In other words, we want to determine whether ...

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