Browsing Fen Bilimleri Enstitüsü by Title

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  • Molecular analyses of germ line methylation patterns and of the common intron 22 inversion mutation in the factor VIII gene 
    El-Maarri, Osman A. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 1998., 1998.)
    The factor VIII gene includes two major mutation hotspots: the intron 22 inversion and transitions at CpG dinucleotides, both of which have been examined in the context of this thesis. A non-radioactive southern blot ...
  • Molecular analysis of Alzheimer's disease and frontotemporal dementia: anovel mutation in the presenilin 1 gene of a Turkish patient with early onset familial Alzheimer's disease 
    Hocaoğlu, Fatma Sinem. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2006., 2006.)
    Alzheimer’s Disease (AD) and Frontotemporal Dementia (FTD) are the most common causes of dementia and death in developed countries. AD is clinically characterized by a progressive decline in cognitive functions. In most ...
  • Molecular analysis of hemoglobinopathies and construction of a database; identification of a novel IVS-II-2 (T-A) mutation 
    Latif, Ayşe. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2006., 2006.)
    Hemoglobinopathies, inherited disorders of the hemoglobin (Hb) molecule, display great molecular and phenotypic diversity. Beta-thalassemia major is considered as the most severe form of hemoglobinopathies and requires ...
  • Molecular analysis of the factor IX gene in the Turkish population 
    Onay, Ü. Venüs. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 1999., 1999.)
    Hemophilia B, the third common hereditary coagulopathy, is very heterogeneous at both phenotypic and genotypic levels. This X-linked recessive disease is caused by the production of either reduced amounts or functionally ...
  • Molecular and cellular development of cortical projection neurons: specification, diversity, and directed differentiation from endogenous progenitors for functional circuit repair 
    Özkan, Abdulkadir. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2016., 2016.)
    Responsible for perception, integration of sensory information, cognitive function, motor control, and consciousness, the complex, yet highly organized, six-layered mammalian neocortex contains distinct classes of neurons. ...
  • Molecular communication in diffusion based channel 
    Akdeniz, Bayram Cevdet. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2018., 2018.)
    This thesis deals with diffusion based molecular communication. Unlike conven tional communication systems, the information is encoded with molecules and these molecules are emitted by nanodevices in a diffusive environment. ...
  • Molecular communications in vessel-like diffusive channels 
    Turan, Meriç. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2019., 2019.)
    Molecular communication via diffusion is based on relaying information over a diffusive channel. The design of this diffusive channel is a vital issue. In this thesis, diffusion in the vessel-like environment, which is composed ...
  • Molecular docking study for novel phosphodiesterase-IV inhibitors 
    Çifci, Gülşah. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2010., 2010.)
    In this study, a molecular docking process for different Phosphodiesterase4 inhibitors is carried out. In the molecular modeling field, the process of docking a ligand to a binding site consists in mimicing the natural ...
  • Molecular dynamics of substrate recognition and co-evolution in HIV-1 protease 
    Özen, Ayşegül. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2008., 2008.)
    Human Immunodeficiency Virus Type 1 (HIV-1) protease recognizes at least ten cleavage sites as its natural substrates. There is little sequence homology between these substrates and they are asymmetric around the cleavage ...
  • Molecular Dynamics simulation of polymeric systems 
    Badur, Bertan Yılmaz. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 1992., 1992.)
    In this thesis, the dynamic and static properties of a polymeric chain in a dilute solution was investigated with the method of molecular dynamics (MD) simulation. We investigated both the equilibrium properties of polymer ...
  • Molecular dynamics study of macromolecular motions and polypeptide helical stabilities in solution 
    Doruker, Pemra. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 1995., 1995.)
    Molecular dynamics simulations have been performed to investigate the relative importance of solvent effect and intramolecular conformational potentials on the properties of polymers in dilute solition. Bead-spring, ...
  • Molecular dynamics study of the interactions between thymoquinone and lipid bilayers 
    Ülgey, Esra. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2022., 2022)
    Thymoquinone, a phytochemical with antitumor activity, and its derivative aminothymoquinone were investigated using Molecular Dynamics (MD) Simulations to understand their interactions with simple and complex bilayer models. ...
  • Molecular dynamics study of water-HBN nanofluid 
    Akıner, Tolga. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2018., 2018.)
    This study considers the molecular simulations of nanofluids and the goal is to investigate the thermomechanical mechanisms in nanoscale thermal transport. The enhanced thermal conductivity and limited shear viscosity ...
  • Molecular genetic analysis of benign epilepsy syndromes 
    Kayserili, Melek Aslı. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2009., 2009.)
    Generalized Epilepsy with Febrile Seizures Plus (GEFS+) and Benign Familial Infantile Seizures (BFIS) are some of the benign epilepsy syndromes. GEFS+ is a collection of phenotypes that show febrile seizures beyond the age ...
  • Molecular genetic analysis of Lafora Disease and Dravet's Syndrome 
    Salar, Seda. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2008., 2008.)
    Lafora Disease (LD), a type of Progressive Myoclonus Epilepsy (PME) and Dravet’s Syndrome (DS), the most severe form in Generalized Epilepsy with Febrile Seizure Plus (GEFS+) spectrum, are debilitating examples of epilepsy ...
  • Molecular modeling of Bcl-xL post-translational modifications and of keteniminium salts 
    Tanrıver, Gamze. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2022., 2022)
    Computational chemistry plays an important role in deciphering the structural proper ties of systems by using different approaches, such as quantum mechanics (QM) and molecular mechanics (MM) and gives insight by mimicking ...
  • Money laundering detection in cryptocurrency networks 
    Erdem, Elif Emine. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2022., 2022)
    This study aims to develop scalable methods to detect suspicious wallets using historical transaction data in cryptocurrency networks such as Ethereum and Bitcoin. Different transaction networks are generated for each ...
  • Monogenic number fields 
    Değirmenci, Pınar. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2022., 2022)
    Determining whether the ring of integers OK of an algebraic number field K of degree n admits a power integral basis is one of the classic problems in algebraic number theory. In other words, we want to determine whether ...
  • Monte Carlo (MC) path generation and small-world network approach to identify functional residues in proteins 
    Armutlulu, Andaç. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2009., 2009.)
    Allosteric mechanism of proteins is crucial for their proper functioning. An important aspect underlying this mechanism is the communication pathways connecting the regulatory and active sites of proteins. Monte Carlo (MC) ...
  • Montmorillonite and modified montmorillonite supported ZnO catalysts 
    Pekcan, Ayşe Hazal. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2015., 2015.)
    The purpose of this study is to prepare ZnO supported montmorillonite based catalysts by using co-precipitation technique. The photocatalytic activities of the as-prepared catalysts are studied for degradation/decolorization ...

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