Browsing Fen Bilimleri Enstitüsü by Title

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  • Investigating the roles of important amino acid residues in GTPase activity of Elongation Factor-Tu (EF-Tu) 
    Gül, Şeref. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2010., 2010.)
    A large number of guanosine triphosphate (GTP)/ guanosine diphosphate (GDP) binding proteins (G-proteins), which usually have intrinsic (and/or stimulated) GTPase activity, are involved in a wide range of cellular regulatory ...
  • Investigation of aging (chronological life span) in S. Cerevisiae by systems biology approaches 
    Yücel, Esra Börklü. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Social Sciences, 2013., 2013.)
    One of the major goals of biological systems research is to improve the human condition and quality of life. Aging is probably the most peculiar phenomenon that a cell, tissue and even an organism experiences. Although it ...
  • Investigation of allosteric coupling in beta-2 adrenergic receptor through molecular dynamics simulations 
    Özgür, Canan. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2014., 2014.)
    The purpose of this thesis is to investigate the allosteric coupling between intra- and extracellular parts of G-protein coupled human β2 adrenergic receptor (β2AR) in the presence of intracellular loop ICL3, which is ...
  • Investigation of antibody-dye conjugates 
    Özer, Enfal. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2019., 2019.)
    Polymeric architectures are widely used in polymer therapeutics for both imaging and drug delivery applications. Design of these polymer drug conjugates consists of three parts: water soluble monomer, linker and the drug ...
  • Investigation of automatically derived subword units for Turkish LVCSR 
    Aksungurlu, Tuncay. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2008., 2008.)
    In this thesis, we performed large vocabulary continuous speech recognition (LVCSR) experiments using language models that are built upon different recognition units in order to create a suitable and successful language ...
  • Investigation of bacterial infection strategies through bacteria-human protein-protein interactions by bioinformatics approaches 
    Gürses, Büşra. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2014., 2014.)
    Infectious diseases, which have been a serious threat for human life in ancient times, is still leading the causes of death and disability worldwide. Pathogens (viruses, bacteria, protozoa, fungi, etc.) express a wide range ...
  • Investigation of beta-lactamase ligand binding in vivo and in silico 
    Kanlıkılıçer, Pınar. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2009., 2009.)
    β-lactam antibiotics are the most commonly used antibiotics due to their high effectiveness, low cost, ease of delivery and minimal side effects. Bacteria have acquired resistance to these antibiotics. One of the mechanisms ...
  • Investigation of cell cycle network of yeast using lab-on-a-chip platform 
    Odabaşı, İrem Ezgi. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2017., 2017.)
    Genome instability has long been implicated as a salient causal factor in aging and age related diseases such as cancer and neurodegeneration. However, the molecular mechanisms associated with genome instability remain ...
  • Investigation of CO hydrogenation catalysts for direct synthesis of dimethyl ether 
    Ekmen, Çiğdem. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2014., 2014.)
    The aim of this work was to prepare and test bi-functional direct DME synthesis catalysts, including commercial ones, involving methanol synthesis and methanol dehydration functions. Catalyst beds were prepared by physical ...
  • Investigation of CO hydrogenation catalysts for producing oxygenated hydrocarbons 
    Kabakçı, Didem Büşra. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2014., 2014.)
    The objective of this study was to test the performance of promoted rhodium catalysts supported on silica for oxygenated hydrocarbon (particularly ethanol) production by CO hydrogenation. Two different catalysts were ...
  • Investigation of CO oxidation kinetics over gold catalysts 
    Ülgüel, Caner. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2011., 2011.)
    This experimental study involves preliminary work conducted over 0.5wt%Au/Al2O3 and kinetic study of low-temperature CO oxidation over 1wt%Au/1.25-wt%MgO/Al2O3 prepared by the homogeneous deposition-precipitation method. ...
  • Investigation of conformational fluctuations in protein dynamics: torsional Gaussian Network Model 
    Özbakır, Harun Ferit. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    Elastic network models based on Normal Mode Analysis (NMA) are very useful in determining the conformational fluctuations that would affect the functions of proteins. Gaussian Network Model (GNM) is proved to be a very ...
  • Investigation of coupling between collective dynamics and function of enzymes 
    Kocaman, Duygu. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2011., 2011.)
    To bridge the structure and function of an enzyme through dynamics is an important problem in protein science. For this aim, the vibrational dynamics for a set of enzymes with different biological units and fold types are ...
  • Investigation of crosstalk between Wnt and Hedgehog signaling pathways 
    Eren, Aysun. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2010., 2010.)
    In the last few years, an intense interest is being shown in the evolutionarily conserved signaling pathways which have crucial roles during embryonic development. The most intriguing factor behind this interest is that ...
  • Investigation of dynamic allostery in motor proteins 
    Kaya, Cihan. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2013., 2013.)
    Allostery is a key concept in regulation of protein function. The communication pathways which are equivalent of the allosteric signaling or energy propagation pathways are the most significant aspect of allosteric mechanism. ...
  • Investigation of dynamic behavior of back to back reinforced soil retaining walls with finite element and artificial neural network 
    Öztürk, Tahir Erdem. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    Back-to-back Mechanically Stabilized Earth (MSE) wall are commonly used for bridge approach embankments. By the means of not only aesthetically pleasing appearance but also satisfactory performance under seismic loading ...
  • Investigation of dynamic behavior of geosynthetic reinforced soil retaining structures under earthquake loads 
    Enünlü, Ali Kasay. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2007., 2007.)
    Due to their advantageous engineering properties and cost effectiveness large numbers of Geosynthetic-Reinforced Soil Retaining Walls (GRS-RWs) are being designed and constructed throughout the world and also in our country. ...
  • Investigation of eccentrically loaded circular concrete-filled tubular (CFT) steel columns by fiber stress analysis (FSA) method 
    Kaptanoğlu, Oğuzhan. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2008., 2008.)
    The composite columns also known by the name “Concrete Filled Tubular (CFT) Steel Columns” have been preferred increasingly in the construction of high-rise buildings, bridges, towers etc. in many countries in the world. ...
  • Investigation of effects of neurological diseases on human brain metabolism: computational systems biology approach 
    Sertbaş, Mustafa. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2013., 2013.)
    The objective of this study is the investigation of the effects of Parkinson’s disease on human brain metabolism by using computational systems biology approach. A new brain metabolic model originated from Çakır et al., ...
  • Investigation of emergence of diversity in language: parent oriented teacher selection 
    Çimentepe, İbrahim. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2016., 2016.)
    In this work, we investigated the emergence of diversity in language. Fundamental game theoretical model for emergence of language has been established and used in several studies. In these studies most basic assumption ...

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