Browsing Fen Bilimleri Enstitüsü by Title

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  • Bozoğlu, Tarık. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2008., 2008.)
    Genes responsible for inherited disorders can be localized on the genome by genetic linkage analysis. Mapping of a disease locus is accomplished by genotyping the family members with polymorphic markers in order to identify ...
  • Bilir, Birdal. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2007., 2007.)
    Pelizaeus-Merzbacher disease (PMD) is a rare inherited leukodystrophy with Xlinked recessive segregation. About 80 per cent of patients with PMD have been associated with mutations of the PLP1 gene on Xq21.3-Xq22 which ...
  • Kaptan, Damla. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    Anatolia’s agricultural biodiversity, which has evolved with the contributions of many different cultures over thousands of years, is today being rapidly eroded as a result of climate change, population growth, globalization ...
  • Ömür, Özgül. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2013., 2013.)
    ALS is the most frequent motor neuron disorder and so far no cure has been developed for this devastating disease. ALS is characterized by the selective loss of both the upper motor neurons of the motor cortex and the lower ...
  • Deniz, Pınar. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2011., 2011.)
    ALS is a late onset, rapidly progressive and ultimately fatal neurodegenerative disease, caused by the loss of motor neurons in the brain and spinal cord. Generally, 5-10% of ALS patients have a family history (fALS), ...
  • İskender, Ceren. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2013., 2013.)
    SOD1 has been a unique target of ALS research as the first identified gene of the disease; since 20 years, SOD1 has not been related to any other disease unlike other ALScausing genes. There are more than 160 mutations ...
  • Tezel, Seden. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2020., 2020.)
    Hereditary Sensory Neuropathy (HSN), predominantly affects sensory nerves and is characterized by sensory loss in addition to muscle weakness, wasting and painless injuries. Autonomic symptoms are commonly associated with ...
  • Demirtaş, Mehmet Yiğit. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2021., 2021.)
    Cryptococcus neoformans is a common opportunistic human pathogen that causes fatal infections, especially for immunocompromised individuals. The computational systems biology approach enables the elucidation of the ...
  • Başıbüyük, Selma. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2019., 2019.)
    The aim of this study is the reconstruction of the genome-scale model of an ecological organism and investigation of its cellular functionality towards toxicity by using computational systems biology approaches. Daphnia ...
  • Afshar, Ulduz Sobhi. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2015., 2015.)
    Interferon Regulatory Factor 4 (IRF4) is a key transcription factor in development and function of immune cells. Also it has been shown that elevated IRF4 expression is a key factor for survival in some myeloid and lymphoid ...
  • Tuna Pesen, Medine. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2016., 2016.)
    Black holes are best known with their strong gravitational eld from which even light can not escape. They are sometimes called spacetime singularities [1, 2]. There are observational evidence of existence of black holes ...
  • Türeli, Sina. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2011., 2011.)
    We start the thesis by covering the geometric formulation of time-independent and time-dependent Lagrangian mechanics and the concept of dynamical symmetry. Then we give two applications. First we review and tie together ...
  • Muğan, Uğurhan. (Thesis (M.S.)- Bogazici University. Institute for Graduate Studies in Science and Engineerig, 1981., 1981.)
  • Sağlam, Pınar. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    This thesis documents a study in which new algorithms are developed for geometry based hand vein biometry. Hand vein patterns are assumed not to change over time except in their size, and they are unique to each individual, ...
  • Köseler, Mahir. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 1984., 1984.)
    The presence of soft layers in Haliç create a great deal of geotechnical problems during the dredging of Haliç. It is necessary to make geotechnical evaluations to prevent critical situations during dredging. The general ...
  • İncircioğlu, Serdar. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2007., 2007.)
    The objective of this research is to modify the fabric of clay by mixing it with paper fibers in different forms. Fiber addition to clay is not a common procedure; however finite length fibers of tire buffings, polypropylene ...
  • Başlantı, Uğur. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2002., 2002.)
    The study aims to clarify the relationship between the characteristics of gifted underachievers at the university level and reasons for underachievement. Underachievement among gifted university students regarding their ...
  • Arı, Oğuz. (Thesis (M.A.) - Bogazici University. Institute for Graduate Studies in the Social Sciences, 2017., 2017.)
    Charcot-Marie-Tooth Type 1X (CMTX1) is the X chromosome linked form of the disease and caused by mutations in the gap junction protein 1 (GJB1) gene. This gene is the second most commonly mutated gene in all CMT forms after ...
  • Alpakut, Gizem. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2020., 2020.)
    Microfluidic chips made of different materials are utilized in numerous examination fields, as they make it possible to screen and study distinctive processes that happen in minuscule sizes. A typical microfluidic device ...
  • Eyüboğlu, Esranur. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2019., 2019.)
    Supplier selection is an important phenomenon for the success of supply chain management in organizations. To survive within a competitive business environment, supply chain departments should be very careful in the matter ...

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