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Biyomedikal Mühendisliği Enstitüsü: Recent submissions

Now showing items 41-60 of 423

The effects of synaptic modulation on the vibrotactile responses of somatosensory cortical neurons studied by microinjection, microstimulation and a computational model

Vardar, Bige. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2019., 2019.)

In this thesis, we studied the eﬀects of synaptic modulation on the vibrotactile responses of somatosensory cortical neurons by three diﬀerent methods: microinjection, microstimulation and a computational model. First, we ...
Application of newborn jaundice determination and design of a noninvasive bilirubinometer

Karamavuş, Yunus. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2019., 2019.)

Newborn jaundice (hyperbilirubinemia), which is seen in 65% of healthy newborns, is usually a harmless condition and passes without any treatment. However, 5% of the jaundiced babies develop kernictures which may cause ...
Optimizing the accuracy of tumor segmentation in pet for radiotherapy planning using blind deconvolution method

Koç, Alpaslan. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2019., 2019.)

Tumor segmentation accuracy greatly aﬀects the eﬀectiveness of radiotherapy procedures. Maximizing the segmentation accuracy has high medical signiﬁcance in order to deliver the highest radiation dose to the target volume ...
Assessment of local muscle deformations using multi-modal imaging and finite element modeling

Pamuk, Uluç. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2019., 2019.)

In vivo assessment of muscle deformations, including inﬂuence of non-muscular tissues such as NVTs, aponeuroses, fasciæ or overlying skin, is key due to functional relevance of tissue connectivity within limb. In integral ...
Design of a dynamic optical property monitoring system: Studying the effect of temperature change

Kara, Ercan. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2018., 2018.)

In laser applications, it is necessary to know the tissue optical properties before the treatment and how they change during the treatment. The optical monitoring system with double-integrating-sphere having a special ...
Thin film based semi-active RF marker desing for interventional MRI devices

Baysoy, Engin. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2018., 2018.)

Compared to the other imaging modalities Magnetic Resonance Imaging (MRI) system has many advantages. There is a great demand to carry out interventional cardiovascular procedures under MRI scanner. However, the lack of ...
Depth assessment of an absorber in a semi-infinite medium by continuous wave diffuse reflectance

Aksel, Ertuğrul Burteçin. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2018., 2018.)

A method to locate an absorber embedded in a semi-in nite turbid medium by spatially-resolved continuous-wave di use re ectance measurements is introduced. The possible of use the method as a priori information in di use ...
Laser sterilization technique for root canal treatment: Investigating the use of thulium fiber laser

Kabaş Sarp, Ayşe Sena. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2018., 2018.)

Conventional endodontic treatment uses a chemomechanical protocol to eliminate all infected debris and take the bacteria out from the root canal in order to prevent the development of persisting apical periodontal inflamation. ...
Modeling of physiolsgical properties of stored human blood by complex impedance measurements

Sezdi, Manâ. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate of Biomedical Engineering, 2006., 2006.)

In this study, the relationship between physiological properties of human blood,namely Na+, K+, Cl- concentrations, pH, 2,3-DPG and ATP, and its electrical parameters,the Cole-Cole parameters- the resistance of the ...
Identification of arterial input function in perfusion imaging with MR angiography-supported semi-automatic method

Büyüksaraç, Bora. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2018., 2018.)

This thesis aims to improve arterial input function (AIF) selection in DSC-MRI by using the information gathered through magnetic resonance angiography (MRA) and cluster analysis of the concentration time curve (CTC) ...
Improvement of ASL basd MR angiography for novel applications

Özyurt, Onur. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2017., 2017.)

In this study, a custom four dimensional arterial spin labeling angiography (4D ASL) sequence and a proof-of-concept software tool to integrate 4D ASL data to routine scanning were implemented. One of the aims of this study ...
Photobiomodulation on human osteoblasts and osteogenic differentiation of adipose-derived stem cells

Bölükbaşı, Gamze. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2017., 2017.)

The present in vitro comparative study evaluated parameters of osteogenesis under the inﬂuence of photobiomodulation (PBM). PBM uses light in the visible and near-infrared spectrum to induce a non-thermal process and to ...
Laser biostimulation and monitorization of wound healing by means of bioimpedance measurements

Solmaz, Hakan. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2016., 2016.)

Wound healing is critically important for the quality of life. Substantial number of patients suffering from non-healing chronic wounds and having serious difficulties in their daily life are reported in wound healing ...
Laser brain surgery with near infrared lasers : investigation of the optimal parameters by real - time temperature monitoring

Tunç, Burcu. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2016., 2016.)

The thermal damage of the surrounding tissue can be an unwanted result of continuous-wave laser irradiation. In order to propose an effective way alternative to conventional surgical techniques, photothermal damage must ...
SOD1 A4V mutation increases Nav1.3 channel excitability on xenopus laevis oocyte

Kubat, Elif. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2016., 2016.)

Amyotrophic lateral sclerosis (ALS) is a lethal, paralytic disease caused by degeneration of motor neurons in the spinal cord, brain stem and motor cortex. Mutations in the gene encoding copper/zinc superoxide dismutase ...
Detailed analysis of voxel based morphometry

Okur, Özlem Özmen. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2016., 2016.)

Voxel Based Morphometry, VBM, is one of the most widely used brain morphometry methods which aims to reveal the structural differences between the brain MR images of different populations. It is a whole brain and fully ...
3-D gamma knife distribution by normoxic gel dosimetry near tissue inhomogeneties

İşbakan, Fatih. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2005., 2005.)

The primary goal in this study was to investigate the three dimensional dose distributions, near the areas of tissue inhomogeneities, in Gamma Knife Radiosurgery with the normoxic gel dosimetry. Following irradiation, when ...
Design of a colimator for breast-specific GAMMA imaging and assesment of nec rate for a pet scanner using monte carlo simulations and response surface methodology

Talat, Didar. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2016., 2016.)

This thesis is composed of two studies that demonstrate the implementation of Monte Carlo (MC) simulations and response surface methodology (RSM) to speci c problems in planar and tomographic nuclear medicine imaging. In ...
Artificial tactile sensation by microstimulation of the hindpaw representation in the primary somatosensory cortex of behaving rats

Devecioğlu, İsmail. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2016., 2016.)

In this thesis, rats were trained to detect the presence or absence of bursts of mechanical sinusoidal vibrations (duration: 0.5 s, zero-to-peak amplitude: 200 m, frequency: 40 Hz) delivered to the volar surface of their ...
Design and application of compartmentalized platforms for neurobiological research

Çetinkaya Fışgın, Aysel. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2016., 2016.)

Conventional culture systems remain inadequate for comprehensive understanding of injury and regeneration in peripheral neurons that extend axons over long distances and through varying extracellular microenvironments. ...

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