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Browsing Boğaziçi Üniversitesi Tezleri by Title

Now showing items 3592-3611 of 7882

Identification and control of nonlinear dynamical systems using neural networks

Efe, Mehmet Önder. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 1996., 1996.)

Artificial neural networks opened a new horizon in many research areas. This understanding, also, brought a new way of thinking into the concept of control. The ever-increasing technological demands steered the control ...
Identification and docking analysis of allatostatin receptor in Carausius morosus

Duan, Burçin. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)

Allatostatin receptors (AlstRs) with their ligands (ASTs) play role in insect development, by inhibiting the production of Juvenile hormone. This thesis project uses the advances in structure-based studies and single-molecule ...
Identification and in vivo analysis of putative Wnt target genes with effective roles in cancer

Even, İpek. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)

One of the most common driving forces in hepatocellular carcinoma (HCC) is the aberrant activation of the Wnt/β-catenin signaling due to the accumulation of mutant β-catenin in the cell. Our group previously detected several ...
Identification of allosteric AKT inhibitors by computational methods

Gürsoy Yılmaz, Oya. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2013., 2013.)

AKT kinases are known to be major contributors to the development of many human cancers according to preclinical data and studies of tumor specimens. Design and development of small molecule inhibitors targeting AKT and ...
Identification of allosteric binding sites of the allatostatin receptor type-C of pine processionary moth

Kahveci, Kübra. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2022., 2022)

G-protein coupled receptors (GPCRs) are cell surface receptors that are consisted of seven-transmembrane α helices. Drugs targeting GPCRs account for one-third of clinically approved drugs; since many drugs target the ...
Identification of arterial input function in perfusion imaging with MR angiography-supported semi-automatic method

Büyüksaraç, Bora. (Thesis (Ph.D.)-Bogazici University. Institute of Biomedical Engineering, 2018., 2018.)

This thesis aims to improve arterial input function (AIF) selection in DSC-MRI by using the information gathered through magnetic resonance angiography (MRA) and cluster analysis of the concentration time curve (CTC) ...
Identification of C17ORF45 protein and the effects of its snornas on cell cycle

Kapıkıran, Vahap. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2013., 2013.)

The Wnt / β-catenin signaling has many important roles in cellular responses and dysregulation of this pathway are linked to tumor formation. Priorly, SAGE and microarray analyses were performed in our laboratory in order ...
Identification of candidate substrates of SIK2 in vitro

Küser, Gamze. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2006., 2006.)

SIK2 is a serine/threonine kinase widely expressed in rat retina and it is postulated to be a potential regulator of FGF signal transduction in retina. The aim of this work is to explore a link between SIK2 and FGF/ERK ...
Identification of drug targets towards prostate canser

Esvap, Elif. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2018., 2018.)

Prostate cancer (Pca) is one of the leading cause of cancer deaths and second common cancer type in men. Identifying novel diagnostics and drug targets speciﬁc for Pca is critical since early detection and treatment are ...
Identification of HB-EGF positive and HB-EGF responsive cell populations in zebrafish olfactory epithelium

Güler, Kardelen. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2022., 2022)

The peripheral olfactory epithelium (OE) is an exception to the limited capacity of the adult nervous system to undergo neurogenesis, which supports structural repair in response to traumatic injury. It continuously and ...
Identification of interaction partners of unzipped, a novel cell adhesion molecule

Akgün, Gamze. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2013., 2013.)

The brain is unquestionably the most sophisticated organ in bodies of many organisms. Establishment of this complex architecture depends on the ability of axons to find their proper targets. On their way to their synaptic ...
Identification of interferon regulatory factor 4 (IRF4) - interacting proteins in melanoma cell lines

Erkan, Ekin Ece. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2015., 2015.)

IRF4 is a member of interferon regulatory factor family of transcription factors. Previously, IRF4 was shown to have regulatory roles in immune cells and B-cell malignancies. In addition, IRF4 was recently shown to be ...
Identification of key transcription factors in glucose sensing pathway in Saccharomyces Cerevisiae

Alazi, Ebru. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2010., 2010.)

In this study, a genome-scale transcriptional regulatory network (TRN) in S. cerevisiae was constructed and integrated with the transcriptome data available in literature for the mutants of the glucose signaling pathway ...
Identification of micropollutants in Ergene river and their biotransformation potential under anaerobic conditions

Emadian, SeyedMehdi. (Thesis (Ph.D.) - Bogazici University. Institute of Environmental Sciences, 2019., 2019.)

Ergene River spans Thrace from northeast to southwest and joins to Maritsa River, then falls to Aegean Sea at Turkey-Greece border. The river suffers pollution from different sources such as industrial and urban discharges, ...
Identification of native conformations of proteins using a low resolution model

Özkan, Ş. Banu. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Sciences and Engineering, 1997., 1997.)

Exhaustive enumeration is performed by using a low resolution model. The secondary structure elements of the proteins are kept as rigid blocks. Large ensembles of decoy structures are generated by rotating the virtual ...
Identification of novel genes involved in planar cell polarity establishment in the Drosophila eye

Koldere, Duygu. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2014., 2014.)

In multicellular organisms proper functioning of tissues requires precise patterning of cells, which is acquired by apical-basal and planar cell polarization. To establish planar cell polarity (PCP), cells have to organize ...
Identification of novel genes involved in the etiology of benign neonatal / infantile epilepsy syndromes and genetic epilepsy with febrile seizures plus (GEFS+)

Usluer, Sunay. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2015., 2015.)

Epilepsy is among the most prevalent episodic neurological disorders. Genetic factors play a major role in the etiology of epilepsy. This thesis included analysis of families with distinct epilepsy phenotypes in order to ...
Identification of novel proteins that interact with BR13, a putative transcriptional target of the Wnt/β-catenin signaling pathway

Akiva, İzzet. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2009., 2009.)

The Wnt/β-catenin signaling pathway is an evolutionary conserved pathway which has important functions in vertebrate early development, axis formation, cellular proliferation and morphogenesis. The activation of this pathway ...
Identification of pathogenic mutations in neurodegenerative disorders: bioinformatic analysis of next generation sequencing data

Kartal, Ece. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2015., 2015.)

Neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis and ataxias belong to a large group of disorders, characterized by progressive neuronal cell death in specific ...
Identification of perturbation-responsive key transcription factors in transcriptional regulatory networks

Kınıkoğlu, Fatma Beste. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2006., 2006.)

In eukaryotic cells, most genes are found to be regulated by various temporary andpermanent transcription factors whose activity levels change as response to perturbations.Discovering the underlying mechanism of complex ...

Now showing items 3592-3611 of 7882

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