Browsing by Subject "Beta lactamases."

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  • Bacterial uptake mechanism of peptides investigated by steered molecular dynamics simulations 
    Akdağ, İhsan Ömür. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2011., 2011.)
    β-lactam antibiotics provide defense against bacterial infections, but the misuse of antibiotics has led to the emergence of bacteria with immunity. One of the major mechanisms of this immunity is bacterial production of ...
  • Beta-lactamase ligand recognition 
    Menekşedağ, Deniz. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2012., 2012.)
    Beta-lactamases hydrolyze the beta-lactam ring of antibiotics, rendering them ineffective. Understanding the inhibitor recognition mechanism of beta-lactamases will give important information toward the fight against ...
  • Investigation of in-vivo inhibition of β-lactamase by β-lactamase inhibitor protein 
    Akkaya, Ayşe Ezgi. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2010., 2010.)
    β-lactam antibiotics, which target transpeptidase enzymes that synthesize the bacterial cell wall, are the most widely utilized antimicrobial agents. However owing to the widespread usage, bacteria acquire resistance to ...
  • Tem-1 β-lactamase activity in the presence of blip in cellular environments 
    Ceylan, Celal. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2010., 2010.)
    β-lactams are an important class of antibiotics used in the treatment of various infections. These antibiotics are the most widely utilized by virtue of their high efficacy, low cost and safety profile. This widespread, ...

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