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Browsing by Subject "Saccharomyces cerevisiae."

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Cell growth and ethanol production characteristics of immobilized S. cerevisiae in a batch system with nutrient recirculation

Birol, Gülnur (Deniz). (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 1992., 1992.)

Recently, there has been world-wide interest in the production of ethanol by fermentation as an alternative to chemical feed stock and as a gasoline extender. Savings in utilities as well as reduction in fixed costs can ...
Comparative analysis of teafs and NP analysis to integrate interactome and transcriptome data to reveal response to C-pulse in Saccharomyces Cerevisiae

Karabekmez, Muhammed Erkan. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2010., 2010.)

Sudden glucose introduction to S. cerevisiae cells grown in carbon limited medium triggers a complex response mechanism. Time series expression data can be used to identify differentially active genes after the C-pulse. ...
Effects of nanocarriers of saccharomyces cerevisiae

Özbek, Özlem. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2019., 2019.)

Nanocarriers have been studied widely owing to their promising features in the field of drug delivery and they improve pharmacokinetic properties, biodistribution, solubility and stability, provide controlled release and ...
Fermentation characteristics of four genetically engineered Saccharomyces cerevisiae strains

Birol (Deniz), Gülnur. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 1997., 1997.)

The production of ethanol from starch has been investigated in four genetically modified Saccharomyces cerevisiae strains (YPG/AB, YA7, YPG/MM and YPB-G). Three of the four strains produce the Aspergillus awamori glucoamylase ...
Identification of key transcription factors in glucose sensing pathway in Saccharomyces Cerevisiae

Alazi, Ebru. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2010., 2010.)

In this study, a genome-scale transcriptional regulatory network (TRN) in S. cerevisiae was constructed and integrated with the transcriptome data available in literature for the mutants of the glucose signaling pathway ...
Identification of perturbation-responsive key transcription factors in transcriptional regulatory networks

Kınıkoğlu, Fatma Beste. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2006., 2006.)

In eukaryotic cells, most genes are found to be regulated by various temporary andpermanent transcription factors whose activity levels change as response to perturbations.Discovering the underlying mechanism of complex ...
Integrated analysis of drug resistance in Saccharomyces Cerevisiae identification of key transcription factors involved in drug resistance

Öç, Şebnem. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2011., 2011.)

In this study, the transcriptome data from the three homozygous deletion mutants, Δqdr3/Δqdr3, Δpdr3/ Δpdr3, and Δho/Δho, of Saccharomyces cerevisiae grown in glucose or ammonium limited continuous cultures were investigated ...
Integrated analysis of metabolome profiles and gene expression in respiratory deficient deletion mutants of Saccharomyces Cerevisiae

Pir, Pınar. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2005., 2005.)

A study on transcriptional and metabolic response of S. cerevisiae cells toenvironmental and genetic perturbations was made. Deletion mutants with BY4743backgound were used. Homozygous deletion mutants ho/ho (reference ...
Integration of interactome and transcriptome data to reveal glucose repression pathway in Saccharomyces Cerevisiae

Hasdemir, Dicle. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2008., 2008.)

Due to glucose’s role as a primary signaling molecule, a change in glucose level immediately stimulates certain elements of the glucose sensing and signaling pathway. This stimulation of the pathway activates the associated ...
Investigation of the effect of plasticity on the prediction of genetic interactions and phenotypes in Saccharomyces Cerevisiae

Dikicioğlu, Duygu. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2011., 2011.)

Prediction of phenotype from genome-scale high-throughput network and component information still remains a challenge for systems based approaches in biological research. The enhancement of our power of prediction of ...
Investigation of the metabolic changes in the adaptive evolution of S. Cerevisiae strains by using genome-scale metabolic models

Çetin, Handan. (Thesis (M.S.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2021., 2021.)

Increasing an organisms’ tolerance level to various stress conditions is one of the most common applications of adaptive laboratory evolution (ALE) experiments which provides high amounts of genomic and experimental data ...
Network topology and dynamic data analysis in saccharomyces cerevisiae

Karabekmez, Muhammed Erkan. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2016., 2016.)

Biological systems which can be represented as networks and graphs are highly dynamic and responsive to environmental and genetic perturbations in a time dependent manner. These networks are hierarchically organized and ...
Production of cystic fibrosis transmembrane conductance regulator (CFTR) protein in recombinant cells

Rende, Deniz. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2004., 2004.)

The application of the recombinant DNA technology is essential for the large scale production of therapeutic proteins and for the elucidation of their structures and function. Cystic Fibrosis Transmembrane Conductance ...
Stoichiometric models in metabolic systems biology of yeast

Çakır, Tunahan. (Thesis (Ph.D.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2006., 2006.)

A system-level analysis of Saccharomyces cerevisiae metabolism was performed through integration of stoichiometric modeling and high-throughput ‘omics’ data. A bridge between metabolic networks and transcriptomics was built ...
Studies on the controlling network of S. Cerevisiae via expression profiling

Cankorur, Ayça. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2007., 2007.)

This study aimed to identify whether the signature of phosphorylation or dephoshorylation of the proteins involved in glucose sensing, signal transduction and glucose repression pathways can be observed at the transcription ...
Studies on the genes controlling glucose signaling in yeast

Şanoviç, Aylin. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2008., 2008.)

This project was aimed to study the phosphorylation or dephosphorylation of the proteins involved in glucose sensing, signal transduction and glucose repression pathways by transcription of genes encoding these proteins. ...
Studies on the role of HAP4, MIG1 and MIG2 in transcriptional control network of Saccharomyces Cerevisiae

Dereli, Elif. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2007., 2007.)

In this study, transcriptional responses of HAP4, MIG1, MIG2 and GSM genes to transient perturbations under glucose and nitrogen limited conditions were investigated in order to understand glucose sensing and signaling ...
Systems-level understanding of copper effect in Saccharomyces cerevisiae

Öç, Şebnem. (Thesis (Ph.D.) - Bogazici University. Institute for Graduate Studies in Science and Engineering, 2019., 2019.)

Copper is a crucial trace element for all living systems as it is required for the proper functioning of several biological processes. Copper homeostasis, which governs the mechanisms of copper uptake, delivery, utilization, ...
The use of different statistical tools in the identification of perturbation-responsive transcription factors in yeast

Çınar, Nil. (Thesis (M.S.)-Bogazici University. Institute for Graduate Studies in Science and Engineering, 2008., 2008.)

S. cerevisiae transcription data, obtained under environmental perturbations, such as 16 different macronutrient (carbon, nitrogen, phosphorus and sulfur) limitation regimes in both aerobic and anaerobic conditions, and ...
Use of flux balance analysis and metabolomics in the analysis of the respiratory pathway in saccharomyces cerevisiae

Dikicioğlu, Duygu. (Thesis (M.S)-Bogazici University.Institute for Graduate Studies in Science and Engineering, 2005., 2005.)

BY4743 and the mutants ?HO, ?QDR3, ?MIG1, ?HAP4, ?QCR7, ?RIP1 and ?CYT1 of S. cerevisiae are investigated to improve knowledge on the regulatory mechanism of respiratory chain and construction of a high ethanol production ...

Browsing by Subject "Saccharomyces cerevisiae."

Browsing by Subject "Saccharomyces cerevisiae."

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